3qyn_ABCD : 3D-footprint complex

structure name	STRUCTURE OF P63 DNA BINDING DOMAIN IN COMPLEX WITH A 22 BASE PAIR A/T RICH RESPONSE ELEMENT CONTAINING 2 BASE PAIR SPACER BETWEEN HALF SITES
reference	Herzberg et al. Proc.Natl.Acad.Sci.USA 108 6456 2011
source	Homo sapiens
experiment	X-ray (resolution=2.50, R-factor=?)
structural superfamily	p53-like transcription factors;
reference complex	3qyn_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3qyn_A interface=182,183,186, spsntdypgphsfdvsfqqsstaksatwtystelkklycqiaktcpiqikvmtpppqgavirampvykkaehvtevvkrcpnhelsrefnegqiappshlirvegnshaqyvedpitgrqsvlvpyeppqvgtefttvlynfmcnsscvggmnrrpiliivtletrdgqvlgrrcfearicACpgRdrkadedsi > 3qyn_B interface=178,179,182, maspsntdypgphsfdvsfqsatwtystelkklycqiaktcpiqikvmtpppqgavirampvykkaehvtevvkrcpnhelsrefnegqiappshlirvegnshaqyvedpitgrqsvlvpyeppqvgtefttvlynfmcnsscvggmnrrpiliivtletrdgqvlgrrcfearicACpgRdrkadedsirk > 3qyn_C interface=183,184,187, aspsntdypgphsfdvsfqqsstaksatwtystelkklycqiaktcpiqikvmtpppqgavirampvykkaehvtevvkrcpnhelsrefnegqiappshlirvegnshaqyvedpitgrqsvlvpyeppqvgtefttvlynfmcnsscvggmnrrpiliivtletrdgqvlgrrcfearicACpgRdrkadedsi > 3qyn_D interface=177,178,181, maspsntdypgphsfdvsfqatwtystelkklycqiaktcpiqikvmtpppqgavirampvykkaehvtevvkrcpnhelsrefnegqiappshlirvegnshaqyvedpitgrqsvlvpyeppqvgtefttvlynfmcnsscvggmnrrpiliivtletrdgqvlgrrcfearicACpgRdrkadedsi
interface signature	ACR/ACR/ACR/ACR

Estimated binding specificities ?

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# IC=10.095 IC/col=0.631 n_of_columns=16

specificity:

A |   0  84   5   0  11  24  24  24  24  24  24  75   0  79   0   0
C |  96   0   7   0  11  24  24  24  24  24  24  11  96   5   0   0
G |   0   5   5  96   5  24  24  24  24  24  24   5   0   7   0  96
T |   0   7  79   0  69  24  24  24  24  24  24   5   0   5  96   0

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updated Mon Sep 9 19:30:48 2024