3r8f_ABCD : 3D-footprint complex

structure name	REPLICATION INITIATOR DNAA BOUND TO AMPPCP AND SINGLE-STRANDED DNA
reference	Duderstadt et al. Nature 478 209 2011
source	Aquifex aeolicus
experiment	X-ray (resolution=3.37, R-factor=?)
structural superfamily	P-loop containing nucleoside triphosphate hydrolases;TrpR-like;
reference complex	3r8f_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3r8f_A interface=80, dflnpkytlenfivgegnrlayevvkealenlgslynpifiygsvgtgkthllqaagneakkrgyrviyssaddfaqamVehlkkgtinefrnmyksvdllllddvqflsgkertqieffhifntlyllekqiilasdrhpqkldgvsdrlvsrfeggilveieldnktrfkiikeklkefnlelrkevidyllentknvreiegkikliklkgfeglerkerkerdklmqivefvanyyavkvedilsdknkrtsearkiamylcrkvcsaslieiarafkrkdhttvihairsveeekrkfkhlvgflekqafdkic > 3r8f_B interface=80, dflnpkytlenfivgegnrlayevvkealenlgslynpifiygsvgtgkthllqaagneakkrgyrviyssaddfaqamVehlkkgtinefrnmyksvdllllddvqflsgkertqieffhifntlyllekqiilasdrhpqkldgvsdrlvsrfeggilveieldnktrfkiikeklkefnlelrkevidyllentknvreiegkikliklkgfeglerkerkerdklmqivefvanyyavkvedilsdknkrtsearkiamylcrkvcsaslieiarafkrkdhttvihairsveeekrkfkhlvgflekqafdkic > 3r8f_C interface=80,84, dflnpkytlenfivgegnrlayevvkealenlgslynpifiygsvgtgkthllqaagneakkrgyrviyssaddfaqamVehlKkgtinefrnmyksvdllllddvqflsgkertqieffhifntlyllekqiilasdrhpqkldgvsdrlvsrfeggilveieldnktrfkiikeklkefnlelrkevidyllentknvreiegkikliklkgfeglerkerkerdklmqivefvanyyavkvedilsdknkrtsearkiamylcrkvcsaslieiarafkrkdhttvihairsveeekrkfkhlvgflekqafdkic > 3r8f_D interface=80,84, dflnpkytlenfivgegnrlayevvkealenlgslynpifiygsvgtgkthllqaagneakkrgyrviyssaddfaqamVehlKkgtinefrnmyksvdllllddvqflsgkertqieffhifntlyllekqiilasdrhpqkldgvsdrlvsrfeggilveieldnktrfkiikeklkefnlelrkevidyllentknvreiegkikliklkgfeglerkerkerdklmqivefvanyyavkvedilsdknkrtsearkiamylcrkvcsaslieiarafkrkdhttvihairsveeekrkfkhlvgflekqafdkic
interface signature	V/V/VK/VK

Estimated binding specificities ?

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# IC=3.142 IC/col=0.314 n_of_columns=10

specificity:

A |  96  24  24  96  24  24  57  24  24  54
C |   0  24  24   0  24  24  13  24  24  13
G |   0  24  24   0  24  24  13  24  24  13
T |   0  24  24   0  24  24  13  24  24  16

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updated Tue Jul 29 22:29:16 2025