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legend  pdf

structure nameNKX2.5 HOMEODOMAIN DIMER BOUND TO ANF-242 DNA
referenceKasahara et al. Biochemistry 51 6312 2012
sourceHomo sapiens
experimentX-ray (resolution=1.70, R-factor=?)
structural superfamilyHomeodomain-like;
reference complex3rkq_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRIQNYK/RIQNY

Estimated binding specificities ?

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# IC=14.051 IC/col=0.740 n_of_columns=19 specificity:   
A |   4   0  73  96   2  91   2  24  24  24  24  24   4  73   0   0   2  11  91
C |   9  86   9   0   1   1   3  24  24  24  24  24  88   9  96   0  11  81   3
G |   2   3  12   0  93   2  91  24  24  24  24  24   2  10   0   0   2   2   2
T |  81   7   2   0   0   2   0  24  24  24  24  24   2   4   0  96  81   2   0
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updated Tue Jul 29 22:46:56 2025