3rkq_AB : 3D-footprint complex

structure name	NKX2.5 HOMEODOMAIN DIMER BOUND TO ANF-242 DNA
reference	Kasahara et al. Biochemistry 51 6312 2012
source	Homo sapiens
experiment	X-ray (resolution=1.70, R-factor=?)
structural superfamily	Homeodomain-like;
reference complex	3rkq_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3rkq_A interface=6,48,51,52,55,56, grrkpRvlfsqaqvyelerrfkqqrylsaperdqlasvlkltstqvkIwfQNrrYKsk > 3rkq_B interface=6,48,51,52,55, grrkpRvlfsqaqvyelerrfkqqrylsaperdqlasvlkltstqvkIwfQNrrYks
interface signature	RIQNYK/RIQNY

Estimated binding specificities ?

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# IC=13.938 IC/col=0.734 n_of_columns=19

specificity:

A |   3   2  74  96   2  91   0  24  24  24  24  24   3  66   0   0   2  10  85
C |  10  82  10   0   0   0   0  24  24  24  24  24  89  10  93   0  10  82   0
G |   0   2  10   0  93   2  96  24  24  24  24  24   2  10   1   0   1   2  10
T |  83  10   2   0   1   3   0  24  24  24  24  24   2  10   2  96  83   2   1

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updated Mon Sep 9 19:47:59 2024