3rkq_AB : 3D-footprint complex

structure name	NKX2.5 HOMEODOMAIN DIMER BOUND TO ANF-242 DNA
reference	Kasahara et al. Biochemistry 51 6312 2012
source	Homo sapiens
experiment	X-ray (resolution=1.70, R-factor=?)
structural superfamily	Homeodomain-like;
reference complex	3rkq_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3rkq_A interface=6,48,51,52,55,56, grrkpRvlfsqaqvyelerrfkqqrylsaperdqlasvlkltstqvkIwfQNrrYKsk > 3rkq_B interface=6,48,51,52,55, grrkpRvlfsqaqvyelerrfkqqrylsaperdqlasvlkltstqvkIwfQNrrYks
interface signature	RIQNYK/RIQNY

Estimated binding specificities ?

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# IC=13.854 IC/col=0.729 n_of_columns=19

specificity:

A |   2   5  73  96   0  10   2  24  24  24  24  24   3   0   0   0  10  12  85
C |   2   2   0   0   0   8   2  24  24  24  24  24  91   2  96   0   8   4   2
G |   0  85  23   0  96  12  91  24  24  24  24  24   0   1   0   0  10  70   6
T |  92   4   0   0   0  66   1  24  24  24  24  24   2  93   0  96  68  10   3

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updated Wed Jun 24 18:12:27 2026