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legend  pdf

structure nameNKX2.5 HOMEODOMAIN DIMER BOUND TO ANF-242 DNA
referenceKasahara et al. Biochemistry 51 6312 2012
sourceHomo sapiens
experimentX-ray (resolution=1.70, R-factor=?)
structural superfamilyHomeodomain-like;
reference complex3rkq_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRIQNYK/RIQNY

Estimated binding specificities ?

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# IC=14.540 IC/col=0.765 n_of_columns=19 specificity:   
A |   0   7  73  96   1  94   0  24  24  24  24  24   1  57   0   0   1  10  95
C |   1  73  11   0   1   0   0  24  24  24  24  24  93  13  95   0  17  84   0
G |   1   1  11   0  94   1  96  24  24  24  24  24   1  13   0   0   4   1   1
T |  94  15   1   0   0   1   0  24  24  24  24  24   1  13   1  96  74   1   0
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updated Mon Jan 5 06:27:00 2026