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structure nameSTRUCTURAL BASIS OF CYTOSOLIC DNA RECOGNITION BY INNATE IMMUNE RECEPTORS
(Interferon-inducible protein AIM2)
referenceJin et al. Immunity 36 561 2012
sourceHomo sapiens
experimentX-ray (resolution=2.50, R-factor=0.202)
structural superfamilyHIN-2000 domain-like;
sequence familyHIN200/IF120x domain;
multimeric complexes3rn2_AB 3rn5_AB
redundant complexes3rn2_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence

No structural evidence for specific binding to DNA (<4 informative columns)


Dendrogram of similar interfaces ?

matrix format
  
  ----DG--YGKT----YTKG----------------------DG--DGDGYGTG--LGLGKGPGRGSG------------STHTYT   L      +----------------------2i0q_A    
                                                                                                  ! 
  --------------------------------------------YG----------------------EG----------NG--HG          !       +-----------------3u58_C    
                                                                                               +--4     +-1 
  --KGFGST----TTDT--TGTGLAFA--QGYGQGIA--------------------------------------------------   L   !  ! +---2 +-----------------3kjp_A    
                                                                                               !  ! !   ! 
  NG----ST------DT----QCHCFATGRGYCQCLGSGKGDG--------------------------------------------     --5  +-3   +-----------------6bwy_A    
                                                                                               !    ! 
  ----------------------------------------------------KTTT--------------KT--FT--STFTST--   L   !    +---------------------4gnx_Z    
                                                                                               ! 
  ------------------------------------------------------------------------KTFTNTQT------   L   +-------------------------6i52_B    
                                                                                             

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updated Fri Sep 13 17:39:02 2024