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structure nameSTRUCTURAL BASIS OF CYTOSOLIC DNA SENSING BY INNATE IMMUNE RECEPTORS
(Gamma-interferon-inducible protein 16)
referenceJin et al. Immunity 36 561 2012
sourceHomo sapiens
experimentX-ray (resolution=2.50, R-factor=0.178)
structural superfamilyHIN-2000 domain-like;
sequence familyHIN200/IF120x domain;
multimeric complexes3rnu_ABCD
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence

No structural evidence for specific binding to DNA (<4 informative columns)


Dendrogram of similar interfaces ?

matrix format
  
  --DGTGYG------YT--------------------------DG--DGDGYGTG----LGLGKGPGRGRGSG------------STHT--YT--   L      +----------------------2i0q_A    
                                                                                                          ! 
  ----------ST--TT----------------------------YT----------YGDG----------STHT--------------YT--RT   L   +--4    +-----------------3kjp_A    
                                                                                                       !  ! +--2 
  NG------ST--TT--DTQCHCFATGYCQCLGSGKGDG--------------------------------------------------------       !  ! !  +-----------------6bwy_A    
                                                                                                       !  +-3 
  --------------------------------------EGKG--YG------------------------EG------------NG--HG----     --5    !  +-----------------3u58_C    
                                                                                                       !    +--1 
  --------------------------FT------------------------KTTTWT--------------KT--FT----STFTST------   L   !       +-----------------4gnx_Z    
                                                                                                       ! 
  --------------------------------------------------------------------------KT--FTNTQT----------   L   +-------------------------6i52_B    
                                                                                                     

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updated Fri Sep 13 17:39:20 2024