3sm4_ABC : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE K131A MUTANT OF LAMBDA EXONUCLEASE IN COMPLEX WITH A 5'-PHOSPHORYLATED 14-MER/12-MER DUPLEX AND MAGNESIUM
reference	Bell et al. Proc.Natl.Acad.Sci.USA 108 11872 2011
source	ENTEROBACTERIA PHAGE LAMBDA
experiment	X-ray (resolution=1.88, R-factor=?)
structural superfamily	Restriction endonuclease-like;
reference complex	3sm4_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 3sm4_A interface= tpdiilqrtgidvraveqgddawhklrlgvitasevhnviakprsgkkwpdmkmsyfhtllaevctgvapevnakalawgkqyendartlfeftsgvnvtespiiyrdesmrtacspdglcsdgnglelacpftsrdfmkfrlggfeaiksaymaqvqysmwvtrknawyfanydprmkreglhyvvierdekymasfdeivpefiekmdealaeigfvfgeqwr > 3sm4_B interface=55,75,77,79,80, shmtpdiilqrtgidvraveqgddawhklrlgvitasevhnviakprsgkkwpdMkmsyfhtllaevctgvapeVnAkALawgkqyendartlfeftsgvnvtespiiyrdesmrtacspdglcsdgnglelacpftsrdfmkfrlggfeaiksaymaqvqysmwvtrknawyfanydprmkreglhyvvierdekymasfdeivpefiekmdealaeigfvfgeqwr > 3sm4_C interface=48, gshmtpdiilqrtgidvraveqgddawhklrlgvitasevhnviakpRsgkkwpdmkmsyfhtllaevctgvapevnakalawgkqyendartlfeftsgvnvtespiiyrdesmrtacspdglcsdgnglelacpftsrdfmkfrlggfeaiksaymaqvqysmwvtrknawyfanydprmkreglhyvvierdekymasfdeivpefiekmdealaeigfvfgeqwr
interface signature	/MVAAL/R

Estimated binding specificities ?

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# IC=1.780 IC/col=0.178 n_of_columns=10

specificity:

A |  19  16  15  24  24  24  22  20  24   0
C |  19  14  15  24  24  24  25  20  24   0
G |  38  52  15  24  24  24  27  22  24  96
T |  20  14  51  24  24  24  22  34  24   0

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updated Wed Jun 24 18:22:47 2026