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structure nameEXPANDING LAGALIDADG ENDONUCLEASE SCAFFOLD DIVERSITY BY RAPIDLY SURVEYING EVOLUTIONARY SEQUENCE SPACE
(Intron-encoded DNA endonuclease I-HjeMI)
referenceScharenberg et al. 'Nucleic 40 4954 2012
sourceTrichoderma reesei
experimentX-ray (resolution=3.00, R-factor=0.285)
structural superfamilyHoming endonucleases;
sequence familyLAGLIDADG endonuclease;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureYSTKYTEERRMRRCSYLNYISDAYTCRKTR

Estimated binding specificities ?

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# IC=15.540 IC/col=0.818 n_of_columns=19 specificity:   
A |   4  96   0   4  96   0   0   6  24  24  24   0   0   0   0  24  12  68  85
C |   0   0   0   0   0   0   0  19  24  24  24   0  96   0   0  24  13   8   3
G |  20   0  96  92   0  96  96  17  24  24  24   0   0   0  86  24   6  10   5
T |  72   0   0   0   0   0   0  54  24  24  24  96   0  96  10  24  65  10   3
scan!

Dendrogram of similar interfaces ?

matrix format

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updated Fri Sep 13 17:49:12 2024