interface graph thumbnail
legend  pdf

structure nameBOTH ZN FINGERS OF GATA1 BOUND TO PALINDROMIC DNA RECOGNITION SITE, P21 CRYSTAL FORM
(Erythroid transcription factor)
referenceWilkinson-White et al. 'To ? ? ?
sourceMus musculus
experimentX-ray (resolution=1.98, R-factor=0.220)
structural superfamilyGlucocorticoid receptor-like DNA-binding domain;
sequence familyGATA zinc finger;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signaturePLRNLTLRNLLRR

Estimated binding specificities ?

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# IC=10.749 IC/col=1.075 n_of_columns=10 specificity:   
A |   0   0  96   0   0  96   0  96  10  64
C |  12   0   0   0  96   0   0   0  10  10
G |  10   0   0   0   0   0  96   0  12  10
T |  74  96   0  96   0   0   0   0  64  12
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: GATA1
AGATAAPubMed3vd6_C(7.16e-05)
GGTGATAAGGPubMed3vd6_C(2.17e-04)
TGATAAPubMed3vd6_C(2.74e-08)

Dendrogram of similar interfaces ?

matrix format
  
  PTLGRGNALCTTLTRGNALA--LTRTRT--   L              +-------------3vd6_C    
                                          +-------1 
  ----------TTLGRGNALA--LT----KT   L   +--2       +-------------3gat_A    
                                       !  ! 
  ------------VTRGNALAFTLTRG----   L --3  +---------------------6gat_A    
                                       ! 
  ----------TTLGRGNALA--LTRT----   L   +------------------------3dfx_B    
                                     

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updated Fri Sep 13 17:49:53 2024