4a04_AB : 3D-footprint complex

structure name	STRUCTURE OF THE DNA-BOUND T-BOX DOMAIN OF HUMAN TBX1, A TRANSCRIPTION FACTOR ASSOCIATED WITH THE DIGEORGE SYNDROME
reference	De Mesmaeker et al. Proteins 80 655 2012
source	HOMO SAPIENS
experiment	X-ray (resolution=2.58, R-factor=?)
structural superfamily	p53-like transcription factors;
reference complex	4a04_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4a04_A interface=29,158,159,175,179, gvsvqlemkalwdefnqlgtemivtkagRrmfptfqvklfgmdpmadymllmdfvpvddkryryafhssswlvagkadpatpgrvhyhpdspakgaqwmkqivsfdklkltnnllddnghiilnsmhryqprfhvvyvdprenfktfvfeetrftavTAyqnhritqlkiasnpFakgFrd > 4a04_B interface=30,167,168,184,188, ggvsvqlemkalwdefnqlgtemivtkagRrmfptfqvklfgmdpmadymllmdfvpvddkryryafhssswlvagkadpatpgrvhyhpdspakgaqwmkqivsfdklkltnnllddnghiilnsmhryqprfhvvyvdprkdsekyaeenfktfvfeetrftavTAyqnhritqlkiasnpFakgFrd
interface signature	RTAFF/RTAFF

Estimated binding specificities ?

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# IC=10.709 IC/col=0.595 n_of_columns=18

specificity:

A |   0  24  24  24   0  96   2   2  24  63  16  14   0   0  24  24  24  96
C |   0  24  24  24  96   0  89  83  24   2  12  16   0   0  24  24  24   0
G |   0  24  24  24   0   0   3   4  24  14  53  54   0  96  24  24  24   0
T |  96  24  24  24   0   0   2   7  24  17  15  12  96   0  24  24  24   0

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updated Mon Jan 5 08:19:40 2026