interface graph thumbnail
legend  pdf

structure nameSTRUCTURE OF THE DNA-BOUND T-BOX DOMAIN OF HUMAN TBX1, A TRANSCRIPTION FACTOR ASSOCIATED WITH THE DIGEORGE SYNDROME
referenceDe Mesmaeker et al. Proteins 80 655 2012
sourceHOMO SAPIENS
experimentX-ray (resolution=2.58, R-factor=?)
structural superfamilyp53-like transcription factors;
reference complex4a04_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRTAFF/RTAFF

Estimated binding specificities ?

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# IC=10.035 IC/col=0.557 n_of_columns=18 specificity:   
A |   0  24  24  24   0  96   2  12  24  56   6  18   0   0  24  24  24  96
C |   0  24  24  24  96   0  74  60  24  18   2   6   0   0  24  24  24   0
G |   0  24  24  24   0   0  10  14  24  16  70  54   0  96  24  24  24   0
T |  96  24  24  24   0   0  10  10  24   6  18  18  96   0  24  24  24   0
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updated Mon Sep 9 21:19:36 2024