4aa6_AB : 3D-footprint complex

structure name	THE OESTROGEN RECEPTOR RECOGNIZES AN IMPERFECTLY PALINDROMIC RESPONSE ELEMENT THROUGH AN ALTERNATIVE SIDE-CHAIN CONFORMATION
reference	Schwabe et al. Structure 3 201 1995
source	HOMO SAPIENS
experiment	X-ray (resolution=2.60, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	4aa6_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4aa6_A interface=22,25,26,29,30, trycavcndyasgyhygvwscEgcKAffKRsihndymcpatnqctidknrrkscqacrlrkcyevgmmk > 4aa6_B interface=22,25,26,29,30, trycavcndyasgyhygvwscEgcKAffKRsiqghdymcpatnqctidknrrkscqacrlrkcyevgmmk
interface signature	EKAKR/EKAKR

Estimated binding specificities ?

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# IC=9.746 IC/col=0.750 n_of_columns=13

specificity:

A |   0   0   6   0  70  24  24  24   5   0  76   0   6
C |   0   0   5  96   5  24  24  24   6   0  10  96  65
G |  96  96   5   0  10  24  24  24   5  96   5   0   5
T |   0   0  80   0  11  24  24  24  80   0   5   0  20

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updated Mon Jan 5 08:30:55 2026