4aa6_AB : 3D-footprint complex

structure name	THE OESTROGEN RECEPTOR RECOGNIZES AN IMPERFECTLY PALINDROMIC RESPONSE ELEMENT THROUGH AN ALTERNATIVE SIDE-CHAIN CONFORMATION
reference	Schwabe et al. Structure 3 201 1995
source	HOMO SAPIENS
experiment	X-ray (resolution=2.60, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	4aa6_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4aa6_A interface=22,25,26,29,30, trycavcndyasgyhygvwscEgcKAffKRsihndymcpatnqctidknrrkscqacrlrkcyevgmmk > 4aa6_B interface=22,25,26,29,30, trycavcndyasgyhygvwscEgcKAffKRsiqghdymcpatnqctidknrrkscqacrlrkcyevgmmk
interface signature	EKAKR/EKAKR

Estimated binding specificities ?

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# IC=10.011 IC/col=0.770 n_of_columns=13

specificity:

A |  18   0   6   0  84  24  24  24   6   0  78   0   0
C |   0   0   6  96   6  24  24  24  12   0   6  96  96
G |  72  96   6   0   6  24  24  24  12  96   6   0   0
T |   6   0  78   0   0  24  24  24  66   0   6   0   0

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updated Wed Jun 24 20:12:17 2026