4aa6_EF : 3D-footprint complex

structure name	THE OESTROGEN RECEPTOR RECOGNIZES AN IMPERFECTLY PALINDROMIC RESPONSE ELEMENT THROUGH AN ALTERNATIVE SIDE-CHAIN CONFORMATION
reference	Schwabe et al. Structure 3 201 1995
source	HOMO SAPIENS
experiment	X-ray (resolution=2.60, R-factor=?)
structural superfamily	Glucocorticoid receptor-like DNA-binding domain;
reference complex	4aa6_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4aa6_E interface=21,24,25,28,29, rycavcndyasgyhygvwscEgcKAffKRsiqgdymcpatnqctidknrrkscqacrlrkcyevgmmk > 4aa6_F interface=22,25,26,29,30, trycavcndyasgyhygvwscEgcKAffKRsiqghndymcpatnqctidkrkscqacrlrkcyevgmmk
interface signature	EKAKR/EKAKR

Estimated binding specificities ?

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# IC=10.335 IC/col=0.795 n_of_columns=13

specificity:

A |  75   0   9   0  73  24  24  24   7   0  96   0   0
C |   7   0   7  96   7  24  24  24   7   0   0  96  96
G |   7  96   7   0   9  24  24  24   7  96   0   0   0
T |   7   0  73   0   7  24  24  24  75   0   0   0   0

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updated Mon Jan 5 08:31:07 2026