structure name | STRUCTURE OF MOUSE DNMT1 (731-1602) BOUND TO HEMIMETHYLATED CPG DNA (DNA cytosine-5-methyltransferase 1) |
reference | Patel et al. Science 335 709 2012 |
source | Mus musculus |
experiment | X-ray (resolution=2.60, R-factor=0.198) |
structural superfamily | S-adenosyl-L-methionine-dependent methyltransferases; |
sequence family | BAH domain; C5 cytosinespecific DNA methylase; |
redundant complexes | 3pt6_B 6w8v_B |
links to other resources | NAKB PDIdb DNAproDB |
protein sequence | |
interface signature | KMRFNHNEMKQ |
Estimated binding specificities ?
contact |
A | 54 24 0 0 13 C | 13 24 0 0 16 G | 13 24 96 96 54 T | 16 24 0 0 13scan! |
Dendrogram of similar interfaces ?
matrix formatKG--------------------MG--RGFGNG------------HGNA------------EGMC--KGQG---- L +--------------------4da4_B ! ------------------SG------------------------------------ECRG----AT-------- ! +----5ciy_A ! +-------3 ------------------VGQG--------------------------FGNGSGEG----SCAGNG-------- L +-----7 ! +----4dkj_A ! ! +--4 ------------CC------NAVGNGPG------ECNCVCRC------------------------------RC ! ! ! ! +6kdb_D ! ! ! ! +-1 --------------------IAVG--PG---------------------------------------------- L ! +----6 +----------2 +6w8b_A +-8 ! ! --------------NT------VT----------------------------------------------LG-- ! ! ! +-6pa7_K ! ! ! ------------------------------------------SG------------------------------ L ! ! +---------------3ubt_A --9 ! ----------NAYA----------YG------------------------------------------------ L ! ! +--------------2ih2_D ! +-----------5 ----------NA------FA--------KG-------------------------------------------- L ! +--------------5hr4_C ! --FTDTITVTAT--KAAA------------WGLG---------------------------------------- L +----------------------------3zh2_C |
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updated Tue Dec 19 08:41:25 2023