interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF THE LARGE FRAGMENT OF DNA POLYMERASE I FROM THERMUS AQUATICUS IN A CLOSED TERNARY COMPLEX WITH 5-(AMINOPENTINYL)- DTTP
(DNA polymerase I, thermostable)
referenceDiederichs et al. J.Am.Chem.Soc. 134 11840 2012
sourceThermus aquaticus
experimentX-ray (resolution=1.90, R-factor=0.181)
structural superfamilyDNA/RNA polymerases;Ribonuclease H-like;
sequence familyDNA polymerase family A; Taq polymerase, exonuclease;
reference complex6fbc_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKTRNNH

Estimated binding specificities ?

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# IC=2.760 IC/col=0.690 n_of_columns=4 specificity:   
A |  11   0   9   0
C |   9  96  11  67
G |  67   0  67  19
T |   9   0   9  10
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updated Sun Jun 28 09:38:02 2026