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structure nameCRYSTAL STRUCTURE OF MBD4 CATALYTIC DOMAIN BOUND TO ABASIC DNA
(Methyl-CpG-binding domain protein 4)
referenceManvilla et al. J.Mol.Biol. 420 164 2012
sourceHomo sapiens
experimentX-ray (resolution=2.76, R-factor=?)
structural superfamilyDNA-glycosylase;
redundant complexes4ew4
reference complex4ofa_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence

No structural evidence for specific binding to DNA (<4 informative columns)


Dendrogram of similar interfaces ?

matrix format
  
  LTVTQTLTNGRGTG----------LG----LC----------------YTNT--KT                                 +4evv_A    
                                                                                    +-----13  
  ----------RGTG----------LC------------------------------                          !      +4dk9_A    
                                                                                 +-21  
  ----------QGCGTA--------LC------------------------------                       !  !     +-1orn_A    
                                                                                 !  +----17  
  ----------QC--RG--------YC------------------------------   L                   !        +-3g0q_A    
                                                                              +-23  
  ----------QTLAHGAT--------------KT----------------------                    !  !        +-3s6i_A    
                                                                              !  !   +---18  
  ----------NA--RA------------FGRC------------------------   L                !  !   !    !  +3i0w_A    
                                                                      +------24  +--20    +-15  
  ----------NCNANARC----------YGRC------------------------            !       !      !       +2xhi_A    
                                                                      !       !      !  
  ----------LG--------------------------------------------       +---25       !      +------3cwt_D    
                                                                 !    !       !  
  --------AGNG----------RCFC------RG------------------RA--       !    !       +-------------3knt_A    
                                                                 !    !  
  --------AA--LA----ITHT----KT----------------------------       !    +---------------------2ofi_A    
                                                                 !  
  --------HTRT------------------------NCSTNARG------------   L   !                              +1k61_B    
                                                                 !                            +-5 
  ------RT----------------------------NT--NAIARG----------   L   !                          +-7 +1puf_B    
                                                                 !                          ! ! 
  ------------------------------------NT--NA--RG----------   L   !                          ! +1b8i_B    
                                                                 !                          !  
  --------------------------------------KGNA--------------   L   !                          !        +2hos_A    
                                                                 !                          !      +-1 
  ------------------------------------IAQTNAMC------------   L   !                          !    +-4 +2h1k_B    
                                                               -26                       +-16    ! ! 
  ------------------------------------IAQCNAYA------------   L   !                       !  !    ! +1nk3_P    
                                                                 !                       !  !    ! 
  ------------------------------------IAKGNA--------------   L   !                       !  !  +-9     +2hdd_A    
                                                                 !                       !  !  ! !   +-2 
  ------------------------------------VASGNA--------------   L   !                       !  !  ! ! +-6 +3cmy_A    
                                                                 !                       !  !  ! ! ! ! 
  ------------------------------------ITQCNAMC------------   L   !                       !  !  ! +-8 +2r5y_A    
                                                                 !                       !  +-14   ! 
  ----------------------------------KTIAQCNA----RT--------   L   !                +-----19     !   +1ig7_A    
                                                                 !                !      !     !  
  ------------------------------------VTQTNAMTKTRT--------   L   !                !      !     !    +1jgg_B    
                                                                 !                !      !     !  +-3 
  --------RA--------------------------ITQCNAMC------------   L   !                !      !     +-12 +1b8i_A    
                                                                 !                !      !        !  
  ----------------------------------KGITQGNAMC------------   L   +---------------22      !        +9ant_B    
                                                                                  !      !  
  ------------------------------------VAQTNA--------------   L                    !      !  +1fjl_B    
                                                                                  !      +-10  
  ----------RT------------------------NCSTNARG------------   L                    !         +1mnm_C    
                                                                                  !  
  ----------------------------------RTVAIANAMCRG----------   L                    !         +1le8_A    
                                                                                  +--------11  
  ------------------------------------IAQCNAYC------------   L                              +3rkq_B    
                                                               

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updated Thu Sep 12 18:58:44 2024