interface graph thumbnail
legend  pdf

structure nameHUMAN DNA POLYMERASE ETA - DNA TERNARY COMPLEX: REACTION IN THE AT CRYSTAL AT PH 6.7 FOR 15 HR, SIDEWAY TRANSLOCATION
(DNA polymerase eta)
referenceNakamura et al. Nature 487 196 2012
sourceHomo sapiens
experimentX-ray (resolution=2.21, R-factor=0.201)
structural superfamilyDNA/RNA polymerases;Lesion bypass DNA polymerase Y-family, little finger domain;
sequence familyimpB/mucB/samB family;
reference complex3jaa_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureFQIRLISLR

Estimated binding specificities ?

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# IC=2.596 IC/col=0.371 n_of_columns=7 specificity:   
A |   0  70  20  24  24  12   9
C |   0   8  20  24  24  60   9
G |   0   8  22  24  24  12  67
T |  96  10  34  24  24  12  11
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updated Thu Sep 12 19:10:10 2024