4er8_A : 3D-footprint complex

structure name	STRUCTURE OF THE REP ASSOCIATES TYROSINE TRANSPOSASE BOUND TO A REP HAIRPIN (TnpArep for protein)
reference	Messing et al. 'Nucleic 40 9964 2012
source	Escherichia coli
experiment	X-ray (resolution=2.60, R-factor=0.228)
structural superfamily	Transposase IS200-like;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4er8_A interface=78,82,97, mseyrryyikggtwfftvnlrnrrsqllttqyqmlrhaiikvkrdrpfeinawvvlpehmhciwtlpegdddfssrwReikKqfthacglkniwqpRfwehairntkdyrhhvdyiyinpvkhgwvkqvsdwpfstfhrdvarglypidwagdvtdfsageriis
interface signature	RKR

Estimated binding specificities ?

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# IC=4.516 IC/col=0.753 n_of_columns=6

specificity:

A |  13   0  24  57   0  96
C |  57   0  24  13   0   0
G |  13  96  24  13   0   0
T |  13   0  24  13  96   0

scan!

Dendrogram of similar interfaces ?

matrix format

  
  SAYTYG--TANGRG------------------------RTKC----NGQGRGWAEGHTAGRGIG   L            +----------------4er8_A    
                                                                         +--------2 
  ------------------------------------RC--------------------------   L   !        !     +----------2itl_B    
                                                                       --3        +-----1 
  ------------------RTRTVT--YT--------------VTQT------------------       !              +----------1uut_A    
                                                                         ! 
  ------TTRT----SAIC------VC--RCNTICRC----------------------------   L   +-------------------------2axy_C

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updated Mon Jun 29 17:48:51 2026