interface graph thumbnail
legend  pdf

structure nameRESTRICTION ENDONUCLEASE DPNI IN COMPLEX WITH TARGET DNA
(TYPE-2 RESTRICTION ENZYME DPNI)
referenceBujnicki et al. 'Nucleic 40 7563 2012
sourceSTREPTOCOCCUS PNEUMONIAE
experimentX-ray (resolution=2.05, R-factor=0.199)
structural superfamilyZinc beta-ribbon;
sequence familyDamreplacing family;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSNHEKRQQ

Estimated binding specificities ?

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# IC=4.475 IC/col=0.895 n_of_columns=5 specificity:   
A |   0  57  13   0   0
C |   0  13  13  96  96
G |  96  13  16   0   0
T |   0  13  54   0   0
scan!

Related DNA sequences reported in the literature ?


sitesourcematches (E-value)
term: DPNI
TCTAGATCTAGAPubMed4esj_A(1.02e-02)
GAATGGATCCTAATGAGATCPubMed4esj_A(1.32e-04)

Dendrogram of similar interfaces ?

matrix format
  
  --SG--------NGHT----ETKG--RGQG--QT------------   L               +--------------------4esj_A    
                                                                +--8 
  QA------------------------------------------NG                !  !                  +-7k63_U    
                                                                !  +------------------3 
  ----RGRTKG------------------------------------   L            !                     +-6lui_A    
                                                                !  
  ----------RC--------------------------------SG                !                   +---7cow_T    
                                                             +-10     +-------------4 
  --------------------------NASTRTHT--ST--------   L         !  !     !             +---3co7_C    
                                                             !  !  +--7 
  --------------------NT--TCTA--------------RT--   L         !  !  !  !        +--------5zux_A    
                                                             !  !  !  +--------5 
  --------------------------------YGRG----------             !  +--9           +--------4wcg_A    
                                                             !     ! 
  --------RC------------------------------------          +-11     !                    +6l9z_S    
                                                          !  !     !    +---------------2 
  --------------------------NA--RAHT--STLT------   L      !  !     +----6               +2a07_J    
                                                          !  !          ! 
  --------------------------NASTRGHTNTSTLT------   L      !  !          +---------------7fj2_B    
                                                       +-12  !  
  ----------------STRGMCTT--RT------------------   L   !  !  !                         +4u0y_B    
                                                       !  !  +-------------------------1 
  ----------------SCRGHC----RT------------QA----   L -13  !                            +5d4s_B    
                                                       !  !  
  ----------------------KT----RG--RGYA----------   L   !  +----------------------------3wts_C    
                                                       !  
  --------------------DCKT----RG--RGYA----------   L   +----------------------------7jsa_J    
                                                     

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updated Thu Sep 12 19:11:30 2024