4esv_ABCDEF : 3D-footprint complex

structure name	A NEW TWIST ON THE TRANSLOCATION MECHANISM OF HELICASES FROM THE STRUCTURE OF DNAB WITH ITS SUBSTRATES
reference	Itsathitphaisarn et al. 'Cell(Cambridge,Mass.)' 151 267 2012
source	Geobacillus stearothermophilus
experiment	X-ray (resolution=3.20, R-factor=?)
structural superfamily	P-loop containing nucleoside triphosphate hydrolases;N-terminal domain of DnaB helicase;
reference complex	4esv_L
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4esv_A interface=311, serippqsieaeqavlgavfldpaalvpaseilipedfyraahqkifhamlrvadrgepvdlvtvtaelaaseqleeiggvsylseladavptaanveyyariveeksvlrrlirtatsiaqdgytredeidvlldeadrkimevsqfknikdilvqtyitgiptgfteldrmtsgfqrsdliivaarpsvgktafalniaqnvatktnenvaifslemsaqqlvmrmlcaegninaqnlrtgkltpedwgkltmamgslsnagiyiddtpsirvsdirakcrrlkqesglgmividylqliqgsgrskeNrqqevseisrslkalarelevpvialsqlsrsveqrqdkrpmmsdiresgsieqdadivaflyrddyynkdsenkniieiiiakqrngpvgtvqlafikeynkfvnl > 4esv_B interface=327,358, serippqsieaeqavlgavfldpaalvpaseilipedfyraahqkifhamlrvadrgepvdlvtvtaelaaseqleeiggvsylseladavptaanveyyariveeksvlrrlirtatsiaqdgytredeidvlldeadrkimevsqrkhsgafknikdilvqtydniemlhngeitgiptgfteldrmtsgfqrsdliivaarpsvgktafalniaqnvatktnenvaifslemsaqqlvmrmlcaegninaqnlrtgkltpedwgkltmamgslsnagiyiddtpsirvsdirakcrrlkqesglgmividylqliqgsgrskeNrqqevseisrslkalarelevpvialsqlsRrpmmsdiresgsieqdadivaflyrddyynkdsenkniieiiiakqrngpvgtvqlafikeynkfvnlerrf > 4esv_C interface=327,329, rippqsieaeqavlgavfldpaalvpaseilipedfyraahqkifhamlrvadrgepvdlvtvtaelaaseqleeiggvsylseladavptaanveyyariveeksvlrrlirtatsiaqdgytredeidvlldeadrkimevsqrkhsgafknikdilvqtydniemlhnrdgeitgiptgfteldrmtsgfqrsdliivaarpsvgktafalniaqnvatktnenvaifslemsaqqlvmrmlcaegninaqnlrtgkltpedwgkltmamgslsnagiyiddtpsirvsdirakcrrlkqesglgmividylqliqgsgrskeNrQqevseisrslkalarelevpvialsqlsrsveqrqdkrpmmsdiresgsieqdadivaflyrddyynkdsenkniieiiiakqrngpvgtvqlafikeynkfvnl > 4esv_D interface=324,326, rippqsieaeqavlgavfldpaalvpaseilipedfyraahqkifhamlrvadrgepvdlvtvtaelaaseqleeiggvsylseladavptaanveyyariveeksvlrrlirtatsiaqdgytredeidvlldeadrkimevsqrkhafknikdilvqtydniemlhnrdgitgiptgfteldrmtsgfqrsdliivaarpsvgktafalniaqnvatktnenvaifslemsaqqlvmrmlcaegninaqnlrtgkltpedwgkltmamgslsnagiyiddtpsirvsdirakcrrlkqesglgmividylqliqgsgrskeNrQqevseisrslkalarelevpvialsqlsrsveqrqdkrpmmsdiresgsieqdadivaflyrddyynkdsenkniieiiiakqrngpvgtvqlafikeynkfvnl > 4esv_E interface=311,313, sieaeqavlgavfldpaalvpaseilipedfyraahqkifhamlrvadrgepvdlvtvtaelaaseqleeiggvsylseladavptaanveyyariveeksvlrrlirtatsiaqdgytredeidvlldeadrkimegafknikdilvqtydniemlhnitgiptgfteldrmtsgfqrsdliivaarpsvgktafalniaqnvatktnenvaifslemsaqqlvmrmlcaegninaqnlrtgkltpedwgkltmamgslsnagiyiddtpsirvsdirakcrrlkqesglgmividylqliqgsgrskeNrQqevseisrslkalarelevpvialsqlsrsveqrqdkrpmmsdiresgsieqdadivaflyrddyynkdsenkniieiiiakqrngpvgtvqlafikeynkfvnl > 4esv_F interface=314,316, ippqsieaeqavlgavfldpaalvpaseilipedfyraahqkifhamlrvadrgepvdlvtvtaelaaseqleeiggvsylseladavptaanveyyariveeksvlrrlirtatsiaqdgytredeidvlldeadrkimevsafknikdilvqtydniemlitgiptgfteldrmtsgfqrsdliivaarpsvgktafalniaqnvatktnenvaifslemsaqqlvmrmlcaegninaqnlrtgkltpedwgkltmamgslsnagiyiddtpsirvsdirakcrrlkqesglgmividylqliqgsgrskeNrQqevseisrslkalarelevpvialsqlsrsveqrqdkrpmmsdiresgsieqdadivaflyrddyynkdsenkniieiiiakqrngpvgtvqlafikeynkfvnl
interface signature	N/NR/NQ/NQ/NQ/NQ

Estimated binding specificities ?

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# IC=7.580 IC/col=0.541 n_of_columns=14

specificity:

A |   0   7   0  24   0  24   7  24   0  24   9  24  24   7
C |   0   9   0  24   0  24   9  24   0  24   7  24  24   7
G |   0   7   0  24   0  24   7  24   0  24   7  24  24   9
T |  96  73  96  24  96  24  73  24  96  24  73  24  24  73

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updated Fri Dec 13 19:26:15 2024