interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF A HMG DOMAIN OF TRANSCRIPTION FACTOR SOX-9 BOUND TO DNA (SOX-9/DNA) FROM HOMO SAPIENS AT 2.77 A RESOLUTION
(TRANSCRIPTION FACTOR SOX-9)
referencePartnership for Stem Cell Biology (STEMCELL)
sourceHOMO SAPIENS
experimentX-ray (resolution=2.77, R-factor=0.248)
structural superfamilyHMG-box;
sequence familyHMG high mobility group box;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRNFMRHNASY

Estimated binding specificities ?

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# IC=5.404 IC/col=0.901 n_of_columns=6 specificity:   
A |  10   0   0   0  10  85
C |  64   0  11   0  10   0
G |  10   0   0   0  64  11
T |  12  96  85  96  12   0
scan!

Dendrogram of similar interfaces ?

matrix format
  
  RTNGFTIARA--NASGST--   L                          +---1j46_A    
                                 +------------------2 
  RCNGFTMARTHTNG--ST--   L       !                  +---6t90_L    
                             +---3 
  RCNTFTMARAHGNAACST--   L   !   !                      +4euw_A    
                           --4   +----------------------1 
  RGNTFTMART--NGRTSA--   L   !                          +7m5w_A    
                             ! 
  RCNAFTIARG--NC--SALT   L   +--------------------------2gzk_A    
                           

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updated Mon Dec 16 23:14:00 2024