4euw_A : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A HMG DOMAIN OF TRANSCRIPTION FACTOR SOX-9 BOUND TO DNA (SOX-9/DNA) FROM HOMO SAPIENS AT 2.77 A RESOLUTION (TRANSCRIPTION FACTOR SOX-9)
reference	Partnership for Stem Cell Biology (STEMCELL)
source	HOMO SAPIENS
experiment	X-ray (resolution=2.77, R-factor=0.248)
structural superfamily	HMG-box;
sequence family	HMG high mobility group box;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4euw_A interface=5,8,10,11,18,29,30,31,34,72, phvkRpmNaFMvwaqaaRrkladqyphlHNAelSktlgklwrllnesekrpfveeaerlrvqhkkdhpdykY
interface signature	RNFMRHNASY

Estimated binding specificities ?

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# IC=5.448 IC/col=0.908 n_of_columns=6

specificity:

A |   0  10  85  85  96  10
C |   0  66   0   1   0  10
G |   0  10  11  10   0  66
T |  96  10   0   0   0  10

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Dendrogram of similar interfaces ?

matrix format

  
  RTNGFTIARA--NASGST--   L                          +---1j46_A    
                                 +------------------2 
  RCNGFTMARTHTNG--ST--   L       !                  +---6t90_L    
                             +---3 
  RCNTFTMARAHGNAACST--   L   !   !                      +4euw_A    
                           --4   +----------------------1 
  RGNTFTMART--NGRTSA--   L   !                          +7m5w_A    
                             ! 
  RCNAFTIARG--NC--SALT   L   +--------------------------2gzk_A

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updated Thu Sep 12 19:11:36 2024