4fgn_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE SV40 LARGE T-ANTIGEN ORIGIN BINING DOMAIN BOUND TO SITE I DNA
reference	Bullock et al. J.Virol. 87 2923 2013
source	Simian virus 40
experiment	X-ray (resolution=3.20, R-factor=?)
structural superfamily	Origin of replication-binding domain, RBD-like;
reference complex	2itl_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4fgn_A interface=20,21,22,23,70,72, edpkdfpsellsflshavfSNRTlacfaiyttkekaallykkimekysvtfisrhnsynhnilffltphRhRvsainnyaqklctfsflickgvnkeylmysaltrdpfsvieeslpgglkehdfn > 4fgn_B interface=19,20,21,22,71, dpkdfpsellsflshavfSNRTlacfaiyttkekaallykkimekysvtfisrhnsynhnilffltphrhRvsainnyaqklctfsflickgvnkeylmysaltrdpfsvieeslpgglkehdf
interface signature	SNRTRR/SNRTR

Estimated binding specificities ?

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# IC=13.992 IC/col=0.777 n_of_columns=18

specificity:

A |   0  80   0   0   0   5  24  24  24  24  24   5   0  81   5   0   0   0
C |   0   5   0   0  96   5  24  24  24  24  24   5   0  10   5   0  96  90
G |  90   6  90  96   0   6  24  24  24  24  24  81  96   0  86  96   0   5
T |   6   5   6   0   0  80  24  24  24  24  24   5   0   5   0   0   0   1

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updated Fri Dec 13 19:29:42 2024