4fx4_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF M. TUBERCULOSIS TRANSCRIPTIONAL REGULATOR MOSR (RV1049) IN COMPEX WITH DNA
reference	Brugarolas et al. J.Biol.Chem. 287 37703 2012
source	Mycobacterium tuberculosis
experiment	X-ray (resolution=3.10, R-factor=?)
structural superfamily	"Winged helix" DNA-binding domain;
reference complex	4fx4_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4fx4_A interface=59,60,61,64,65, ecacyttrraarqlgqaydralrpsgltntqfstlavislsegsdltmselaarigveRTTltRNlevmrrdglvrvmagckrieltakgraalqkavplwrgvqaevtawprvrrdianlgqaaeac > 4fx4_B interface=54,55,56,59,60,79, ecacyttrraarqlgqaydralrpsgltntqfstlavislstmselaarigveRTTltRNlevmrrdglvrvmagadaRckrieltakgraalqkavplwrgvqaevtasvgdwprvrrdianlgqaaeacrl
interface signature	RTTRN/RTTRNR

Estimated binding specificities ?

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# IC=15.149 IC/col=0.891 n_of_columns=17

specificity:

A |  69   7  24   0   0   0   0   0  64  24  24   5  90   0  96   0   0
C |  11  11  24  96   0   0   0   0  11  24  24   5   6  96   0  96   0
G |  11  11  24   0  96   0  96   0  16  24  24   7   0   0   0   0  96
T |   5  67  24   0   0  96   0  96   5  24  24  79   0   0   0   0   0

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updated Mon Jan 5 08:59:12 2026