4fx4_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF M. TUBERCULOSIS TRANSCRIPTIONAL REGULATOR MOSR (RV1049) IN COMPEX WITH DNA
reference	Brugarolas et al. J.Biol.Chem. 287 37703 2012
source	Mycobacterium tuberculosis
experiment	X-ray (resolution=3.10, R-factor=?)
structural superfamily	"Winged helix" DNA-binding domain;
reference complex	4fx4_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4fx4_A interface=59,60,61,64,65, ecacyttrraarqlgqaydralrpsgltntqfstlavislsegsdltmselaarigveRTTltRNlevmrrdglvrvmagckrieltakgraalqkavplwrgvqaevtawprvrrdianlgqaaeac > 4fx4_B interface=54,55,56,59,60,79, ecacyttrraarqlgqaydralrpsgltntqfstlavislstmselaarigveRTTltRNlevmrrdglvrvmagadaRckrieltakgraalqkavplwrgvqaevtasvgdwprvrrdianlgqaaeacrl
interface signature	RTTRN/RTTRNR

Estimated binding specificities ?

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# IC=15.406 IC/col=0.906 n_of_columns=17

specificity:

A |   0   0   0   0   0  75  24  24   6  96   0  96   0   0  24  75   6
C |  96   0   0   0   0   9  24  24   6   0  96   0  96   0  24   6  13
G |   0  96   0  96   6   6  24  24   9   0   0   0   0  96  24   9   9
T |   0   0  96   0  90   6  24  24  75   0   0   0   0   0  24   6  68

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updated Wed Jul 30 01:00:30 2025