4jbm_A : 3D-footprint complex

structure name	STRUCTURE OF MURINE DNA BINDING PROTEIN BOUND WITH DS DNA (Interferon-inducible protein AIM2)
reference	Crowley et al. 'Cell 23 855 2013
source	Mus musculus
experiment	X-ray (resolution=2.22, R-factor=0.237)
structural superfamily	HIN-2000 domain-like;
sequence family	HIN200/IF120x domain;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4jbm_A interface=86,89, mdplvvtvlkainpfecegrqeifhatvatetdfffvkvlnaqfkdkfipkrtikisnylwhsnfmevtsssvvvdvesnhevpnNvvKraretprisklkiqpcgtivnglfkvqkiteekdrvlygihdktgtmevlvlgnpsktkceegdkirltffevskngvkiqlksgpcsffkvikaakpktd
interface signature	NK

Estimated binding specificities ?

contact

# IC=2.340 IC/col=0.585 n_of_columns=4

specificity:

A |   7   9   7   7
C |   7  73   9  75
G |  75   7  73   7
T |   7   7   7   7

scan!

Dendrogram of similar interfaces ?

matrix format

  
  --DGTGYGKT--------YTKG----------------------DG--DGDGYGTG--LGLGPGRGRGSG------------STHTYT   L      +----------------------2i0q_A    
                                                                                                    ! 
  ----------------------------------------------YG--------------------EG------------NG--HG          !       +-----------------3u58_C    
                                                                                                 +--4     +-1 
  KGFG------ST--TTDT--TGTGLAFA--QGYGQGIA--------------------------------------------------   L   !  ! +---2 +-----------------3kjp_A    
                                                                                                 !  ! !   ! 
  ------ST----TT--DT----QCHCFATGRGYCQCLGSGKGDG--------------------------------------------     --5  +-3   +-----------------6bwy_A    
                                                                                                 !    ! 
  ------------------------------------------------------KTTT------------KT----FT--STFTST--   L   !    +---------------------4gnx_Z    
                                                                                                 ! 
  ------------------------------------------------------------------------KTFT--NTQT------   L   +-------------------------6i52_B

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updated Fri Sep 13 18:24:59 2024