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structure nameCRYSTAL STRUCTURE OF THE I-LTRWI LAGLIDADG HOMING ENDONUCLEASE BOUND TO TARGET DNA.
(LAGLIDADG homing endonuclease)
referenceStoddard et al. 'To ? ? ?
sourceLeptographium truncatum
experimentX-ray (resolution=2.68, R-factor=0.200)
structural superfamilyHoming endonucleases;
sequence familyLAGLIDADG endonuclease;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSNVHTNALYEAYNSDTKKSCFSYSKSAQKTRERADT

Estimated binding specificities ?

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# IC=21.367 IC/col=1.017 n_of_columns=21 specificity:   
A |   0   0  96  96  64   8  96  96   0  96  24  24   0   0   0   0  96   0   4  64   0
C |   4   0   0   0   8  12   0   0  96   0  24  24  96   0   0  96   0  92  12  12  96
G |   0   0   0   0  12  12   0   0   0   0  24  24   0   0   0   0   0   0   8   8   0
T |  92  96   0   0  12  64   0   0   0   0  24  24   0  96  96   0   0   4  72  12   0
scan!

Dendrogram of similar interfaces ?

matrix format

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updated Sun Aug 3 08:14:12 2025