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structure nameCRYSTAL STRUCTURE OF THE I-LTRWI LAGLIDADG HOMING ENDONUCLEASE BOUND TO TARGET DNA.
(LAGLIDADG homing endonuclease)
referenceStoddard et al. 'To ? ? ?
sourceLeptographium truncatum
experimentX-ray (resolution=2.68, R-factor=0.200)
structural superfamilyHoming endonucleases;
sequence familyLAGLIDADG endonuclease;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureSNVHTNALYEAYNSDTKKSCFSYSKSAQKTRERADT

Estimated binding specificities ?

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# IC=21.283 IC/col=1.013 n_of_columns=21 specificity:   
A |   3   0  96  96  65   9  96  96   0  96  24  24   0   0   0   0  96   0   3  65   0
C |   6   0   0   0   7  11   0   0  96   0  24  24  96   0   0  96   0  92  11   7  96
G |   3   0   0   0  11  11   0   0   0   0  24  24   0   0   0   0   0   1   3  11   0
T |  84  96   0   0  13  65   0   0   0   0  24  24   0  96  96   0   0   3  79  13   0
scan!

Dendrogram of similar interfaces ?

matrix format

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updated Sat Jan 10 07:14:48 2026