| structure name | CRYSTAL STRUCTURE OF LIGANDED HRXR-ALPHA/HLXR-BETA HETERODIMER ON DNA (LIVER X NUCLEAR RECEPTOR BETA) |
| reference | Gustafsson et al. Nat.Struct.Mol.Biol. 21 277 2014 |
| source | HOMO SAPIENS |
| experiment | X-ray (resolution=3.10, R-factor=0.186) |
| structural superfamily | Nuclear receptor ligand-binding domain;Glucocorticoid receptor-like DNA-binding domain; |
| sequence family | Ligandbinding domain of nuclear hormon; Zinc finger, C4 type two domains; |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | APEKRR |
Estimated binding specificities ?
readout + contact |  |
A | 67 0 0 11 0 69 C | 11 0 0 9 96 9 G | 9 96 96 9 0 9 T | 9 0 0 67 0 9scan! |
Related DNA sequences reported in the literature ?
| site | source | matches (E-value) |
|---|---|---|
| term: HRXR | ||
| AGGTCA | PubMed | 4nqa_I(3.91e-11), 4nqa_AB(2.35e-07), 4nqa_HI(2.36e-07) |
Dendrogram of similar interfaces ?
matrix formatACPT--ECKA--RGRG------------ L +---------------------4nqa_I ! ------EAKG--RTRTRT---------- ! +4umm_E ! +-----------1 ------EAKG--RTRTRT---------- ! ! +2han_B +------8 ! ----CAECKG--KGRG------------ L ! ! +-6 +---6l6q_B ! ! ! ! ! ------DGKG--RTRG------------ L ! ! ! ! ! +3cbb_A ! ! ! +-------5 +-2 ------ECKG--KGRG--RC-------- L ! ! ! ! +-3 +2ff0_A --9 +-------7 ! ! ! --------KAVA--RA------------ L ! ! +--4 +5e69_A ! ! ! ------ETKGAT--RG------------ L ! ! +1lat_A ! ! --------KGVT--RG------------ L ! +-------------5emp_A ! --------------------RAIAQTNA L +----------------------------6es3_K |
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updated Tue Dec 17 00:02:41 2024