interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF HUMAN POLYMERASE ETA INSERTING DGTP OPPOSITE AN 8-OXOG CONTAINING DNA TEMPLATE
(DNA polymerase eta)
referencePatra et al. J.Biol.Chem. 289 16867 2014
sourceHomo sapiens
experimentX-ray (resolution=1.72, R-factor=0.187)
structural superfamilyDNA/RNA polymerases;Lesion bypass DNA polymerase Y-family, little finger domain;
sequence familyimpB/mucB/samB family;
reference complex3jaa_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRSNLRMF

Estimated binding specificities ?

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# IC=3.529 IC/col=0.588 n_of_columns=6 specificity:   
A |  96   6  21  24  10   2
C |   0   6  21  24  63   1
G |   0   6  31  24  13  92
T |   0  78  23  24  10   1
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updated Tue Dec 17 00:03:41 2024