interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF HUMAN POLYMERASE ETA INSERTING DGTP OPPOSITE AN 8-OXOG CONTAINING DNA TEMPLATE
(DNA polymerase eta)
referencePatra et al. J.Biol.Chem. 289 16867 2014
sourceHomo sapiens
experimentX-ray (resolution=1.72, R-factor=0.187)
structural superfamilyDNA/RNA polymerases;Lesion bypass DNA polymerase Y-family, little finger domain;
sequence familyimpB/mucB/samB family;
reference complex3jaa_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRSNLRMF

Estimated binding specificities ?

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# IC=3.582 IC/col=0.597 n_of_columns=6 specificity:   
A |   1  10  24  23  78   0
C |  92  10  24  31   6   0
G |   1  66  24  21   6   0
T |   2  10  24  21   6  96
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updated Thu Sep 12 19:53:36 2024