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legend  pdf

structure nameSTRUCTURE OF HUMAN PARP-1 BOUND TO A DNA DOUBLE STRAND BREAK IN COMPLEX WITH (2R)-5-FLUORO-2-METHYL-2,3-DIHYDRO-1-BENZOFURAN-7- CARBOXAMIDE
(POLY ADP-RIBOSE POLYMERASE 1)
referenceSteffen et al. J.Med.Chem. 57 5579 2014
sourceHOMO SAPIENS
experimentX-ray (resolution=3.31, R-factor=0.304)
structural superfamilyGlucocorticoid receptor-like DNA-binding domain;
sequence familyPolyADPribose polymerase and DNALigase Z; PADR1 NUC008 domain;
multimeric complexes4opx_AD 4oqa_AD 4oqb_AD
redundant complexes4oqa 4oqb
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence

No structural evidence for specific binding to DNA (<4 informative columns)


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updated Fri Sep 13 18:35:18 2024