4pu3_ABCD : 3D-footprint complex

structure name	SHEWANELLA ONEIDENSIS MR-1 TOXIN ANTITOXIN SYSTEM HIPA, HIPB AND ITS OPERATOR DNA COMPLEX (SPACE GROUP P212121)
reference	Elegheert et al. 'Nucleic 42 10134 2014
source	SHEWANELLA ONEIDENSIS
experiment	X-ray (resolution=3.39, R-factor=?)
structural superfamily	lambda repressor-like DNA-binding domains;
reference complex	4pu3_A 4pu3_C
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4pu3_A interface= tlemhlgdlmigelsfdatadtfavhytkdwqqsgfplsptipldgtgtsnqismflvnllpenkgldylieslgvskgntfaliraigldtagaiafvpkgallpetqlrpikaeeviqriedptmwpmeiwdgkprlvagvqpklnlfyngkefafaegtlssthivkfekyhhlvinefitmrlakvlgmnvanvdivhfgrykalcverfdrrnipgeqrvlrrhivdscqalgfsvskkyernfgtgrdvkdiregvsfnrlfslaakcrnpvaakqdmlqwalfnlltgnadahgknysffmtpsgmeptpwydlvsvdmyedfeqqlamaiddefdpnsiyayqlaafmdglglprnllisnltriarripqaiaevilmlppldedeasfvahyktqllarcerylgfvdevrdvev > 4pu3_B interface= tlemhlgdlmigelsfdatadtfavhytkdwqqsgfplsptipldgtgtsnqismflvnllpenkgldylieslgvskgntfaliraigldtagaiafvpkgallpetqlrpikaeeviqriedptmwpmeiwdgkprlvagvqpklnlfyngkefafaegtlssthivkfekyhhlvinefitmrlakvlgmnvanvdivhfgrykalcverfdrrnipgeqrvlrrhivdscqalgfsvskkyernfgtgrdvkdiregvsfnrlfslaakcrnpvaakqdmlqwalfnlltgnadahgknysffmtpsgmeptpwydlvsvdmyedfeqqlamaiddefdpnsiyayqlaafmdglglprnllisnltriarripqaiaevilmlppldedeasfvahyktqllarcerylgfvdevrdvev > 4pu3_C interface=26,36,37,38,41,50, imasplnqqslgllikerrksaaltQdvaamlcgvTKKtlIrvekgedvYistvfkildglgidivsagwy > 4pu3_D interface=36,37,38,41,50, imasplnqqslgllikerrksaaltqdvaamlcgvTKKtlIrvekgedvYistvfkildglgidivsagwy
interface signature	//QTKKIY/TKKIY

Estimated binding specificities ?

readout + contact

# IC=7.604 IC/col=0.507 n_of_columns=15

specificity:

A |   0  24   0   8  24  24  24  24  24  24  96   8  16   0   0
C |   0  24   0   8  24  24  24  24  24  24   0  56  48  96   0
G |   0  24   0  72  24  24  24  24  24  24   0  16  16   0   0
T |  96  24  96   8  24  24  24  24  24  24   0  16  16   0  96

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updated Mon Jan 5 10:48:17 2026