interface graph thumbnail
legend  pdf

structure nameZINC FINGER REGION OF MLL2 IN COMPLEX WITH CPG DNA
(HISTONE-LYSINE N-METHYLTRANSFERASE 2B)
referenceStructural Genomics Consortium (SGC)
sourceHOMO SAPIENS
experimentX-ray (resolution=2.15, R-factor=0.228)
sequence familyCXXC zinc finger domain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRKQ

Estimated binding specificities ?

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# IC=3.261 IC/col=0.815 n_of_columns=4 specificity:   
A |   4   4   1  18
C |  86   3   0  18
G |   4  88  95  20
T |   2   1   0  40
scan!

Dendrogram of similar interfaces ?

matrix format
  
  --RC------KGQG------   L         +-----4pzi_A    
                             +-----2 
  ----------RGQG--MTRT   L   !     +-----5w9q_B    
                           --3 
  --------KTKGQC------   L   !           +4nw3_A    
                             +-----------1 
  RC--NTICKGKGQGKT----   L               +2kkf_A    
                           

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updated Sat Aug 2 07:09:00 2025