interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF HUMAN POLYMERASE ETA INSERTING DGMPNPP OPPOSITE DNA TEMPLATE CONTAINING AN ABASIC SITE
(DNA polymerase eta)
referencePatra et al. J.Biol.Chem. 290 8028 2015
sourceHomo sapiens
experimentX-ray (resolution=1.81, R-factor=0.170)
structural superfamilyDNA/RNA polymerases;Lesion bypass DNA polymerase Y-family, little finger domain;
sequence familyimpB/mucB/samB family;
reference complex3jaa_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRSNLRM

Estimated binding specificities ?

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# IC=2.635 IC/col=0.439 n_of_columns=6 specificity:   
A |   0  11  24  24  67  11
C |  96   9  24  24   9   9
G |   0  67  24  24   9   9
T |   0   9  24  24  11  67
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updated Sun Jun 28 11:09:53 2026