4roc_AB : 3D-footprint complex

structure name	HUMAN TFIIB-RELATED FACTOR 2 (BRF2) AND TBP BOUND TO U6#2 PROMOTER
reference	Guthertz et al. 'Cell(Cambridge,Mass.)' 163 1375 2015
source	HOMO SAPIENS
experiment	X-ray (resolution=1.90, R-factor=?)
structural superfamily	TATA-box binding protein-like;Cyclin-like;Zinc beta-ribbon;
reference complex	1cdw_A 8ity_V
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4roc_A interface=44,46,196, vsrsqqrglrrvrdlcrvlqlpptfedtavayyqqayrhsgirAaRlqkkevlvgccvlitcrqhnwpltmgaictllyadldvfsstymqivkllgldvpslclaelvktycssfklfqaspsvpakyvedkekmlsrtmqlvelanetwlvtgrhplpvitaatflawqslqpadrlscslarfcklanvdlpYpassrlqellavllrmaeqlawlrvlrldkrsvvkhigdllqhrqslvrsafrdlllppcmlkspkricpvppvstvtgdenisdseieqylrtpqevrdfqraqa > 4roc_B interface=11,13,41,56,58,64,66,101,103,132,133,147,149,155,157, gpsgivpqlqNiVstvnlgckldlktialrarnaeynpkrFaavimrireprttaLiFssgkmVcTgakseeqsrlaarkyarvvqklgfpakfldfkiqNmVgscdvkfpirleglvlthqqfssyepelFPgliyrmikprivlLiFvsgkvVlTgakvraeiyeafeniypilkg
interface signature	ARY/NVFLFVTNVFPLFVT

Estimated binding specificities ?

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# IC=11.283 IC/col=0.752 n_of_columns=15

specificity:

A |   5   0  24  24   5   0  96  96  96  79   0  73  24  24  11
C |   1   5  24  24   5   0   0   0   0   7   0  13  24  24   5
G |  90  84  24  24   7   0   0   0   0   5   0   5  24  24   5
T |   0   7  24  24  79  96   0   0   0   5  96   5  24  24  75

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updated Mon Jan 5 11:03:05 2026