4roc_AB : 3D-footprint complex

structure name	HUMAN TFIIB-RELATED FACTOR 2 (BRF2) AND TBP BOUND TO U6#2 PROMOTER
reference	Guthertz et al. 'Cell(Cambridge,Mass.)' 163 1375 2015
source	HOMO SAPIENS
experiment	X-ray (resolution=1.90, R-factor=?)
structural superfamily	TATA-box binding protein-like;Cyclin-like;Zinc beta-ribbon;
reference complex	1cdw_A 8ity_V
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4roc_A interface=44,46,196, vsrsqqrglrrvrdlcrvlqlpptfedtavayyqqayrhsgirAaRlqkkevlvgccvlitcrqhnwpltmgaictllyadldvfsstymqivkllgldvpslclaelvktycssfklfqaspsvpakyvedkekmlsrtmqlvelanetwlvtgrhplpvitaatflawqslqpadrlscslarfcklanvdlpYpassrlqellavllrmaeqlawlrvlrldkrsvvkhigdllqhrqslvrsafrdlllppcmlkspkricpvppvstvtgdenisdseieqylrtpqevrdfqraqa > 4roc_B interface=11,13,41,56,58,64,66,101,103,132,133,147,149,155,157, gpsgivpqlqNiVstvnlgckldlktialrarnaeynpkrFaavimrireprttaLiFssgkmVcTgakseeqsrlaarkyarvvqklgfpakfldfkiqNmVgscdvkfpirleglvlthqqfssyepelFPgliyrmikprivlLiFvsgkvVlTgakvraeiyeafeniypilkg
interface signature	ARY/NVFLFVTNVFPLFVT

Estimated binding specificities ?

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# IC=11.401 IC/col=0.760 n_of_columns=15

specificity:

A |  78  24  24   6  96   6   0   0   0  96  84  24  24   6   0
C |   6  24  24   6   0   6   0   0   0   0   6  24  24  78  90
G |   6  24  24   6   0   6   0   0   0   0   6  24  24   6   0
T |   6  24  24  78   0  78  96  96  96   0   0  24  24   6   6

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updated Wed Jul 30 02:50:23 2025