4roe_AB : 3D-footprint complex

structure name	HUMAN TFIIB-RELATED FACTOR 2 (BRF2) AND TBP BOUND TO RPPH1 PROMOTER
reference	Guthertz et al. 'Cell(Cambridge,Mass.)' 163 1375 2015
source	HOMO SAPIENS
experiment	X-ray (resolution=2.20, R-factor=?)
structural superfamily	TATA-box binding protein-like;Cyclin-like;Zinc beta-ribbon;
reference complex	1cdw_A 8ity_V
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4roe_A interface=45,47,197, qvsrsqqrglrrvrdlcrvlqlpptfedtavayyqqayrhsgirAaRlqkkevlvgccvlitcrqhnwpltmgaictllyadldvfsstymqivkllgldvpslclaelvktycssfklfqaspsvpakyvedkekmlsrtmqlvelanetwlvtgrhplpvitaatflawqslqpadrlscslarfcklanvdlpYpassrlqellavllrmaeqlawlrvlrldkrsvvkhigdllqhrqslvrsafrdlllppcmlkspkricpvppvstvtgdenisdseieqylrtpqevrdfqraqaarqa > 4roe_B interface=10,12,40,41,55,57,63,65,100,102,131,132,146,148,154,156, psgivpqlqNiVstvnlgckldlktialrarnaeynpkrFAavimrireprttaLiFssgkmVcTgakseeqsrlaarkyarvvqklgfpakfldfkiqNmVgscdvkfpirleglvlthqqfssyepelFPgliyrmikprivlLiFvsgkvVlTgakvraeiyeafeniypilkg
interface signature	ARY/NVFALFVTNVFPLFVT

Estimated binding specificities ?

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# IC=12.382 IC/col=0.825 n_of_columns=15

specificity:

A |  54  24  24   0   0   0  96   0  96  96  12  24   6   0   6
C |   6  24  24  96   0   0   0   0   0   0  12  24  12  12  72
G |  30  24  24   0   0   0   0   0   0   0  66  24   0   0   6
T |   6  24  24   0  96  96   0  96   0   0   6  24  78  84  12

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updated Mon Jan 5 11:03:56 2026