interface graph thumbnail
legend  pdf

structure nameFOXP3 FORMS A DOMAIN-SWAPPED DIMER TO BRIDGE DNA
(Forkhead box protein P3)
referenceChen et al. 'Nucleic 43 1268 2015
sourceHomo sapiens
experimentX-ray (resolution=3.40, R-factor=0.196)
structural superfamily"Winged helix" DNA-binding domain;
sequence familyFork head domain;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureNRHSL

Estimated binding specificities ?

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# IC=4.007 IC/col=0.801 n_of_columns=5 specificity:   
A |  67   9   0   0   9
C |   9  11   0   0   9
G |  11   9   0   0  69
T |   9  67  96  96   9
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updated Sun Jun 28 11:16:32 2026