4wls_AB : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF THE METAL-FREE (REPRESSOR) FORM OF E. COLI CUER, A COPPER EFFLUX REGULATOR, BOUND TO COPA PROMOTER DNA
reference	Canalizo-Hernandez et al. Science 349 877 2015
source	Escherichia coli DH5[alpha] / Escherichia coli DH5[alpha] / Escherichia coli DH5[alpha] / Escherichia coli DH5[alpha]
experiment	X-ray (resolution=2.10, R-factor=?)
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4wls_A interface=15,18,19,36, mnisdvakitgltsKaiRFyeekglvtppmrsengYrtytqqhlneltllrqarqvgfnleesgelvnlfndpqrhsadvkrrtlekvaeierhieelqsmrdqllalana > 4wls_B interface=15,18,19,36, mnisdvakitgltsKaiRFyeekglvtppmrsengYrtytqqhlneltllrqarqvgfnleesgelvnlfndpqrhsadvkrrtlekvaeierhieelqsmrdqllalana
interface signature	KRFY/KRFY

Estimated binding specificities ?

readout + contact

# IC=12.161 IC/col=0.811 n_of_columns=15

specificity:

A |   3   0   3   0   5  24  24   0   3   0   0  81  60  24   3
C |  87  96  87  96  12  24  24  96   3   0   0   3   9  24   4
G |   3   0   3   0   3  24  24   0   4  96  96   9  15  24  86
T |   3   0   3   0  76  24  24   0  86   0   0   3  12  24   3

scan!

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updated Mon Jan 5 11:16:19 2026