4wuz_ABC : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF LAMBDA EXONUCLEASE IN COMPLEX WITH DNA AND CA2+
reference	Bell et al. Biochemistry 53 7415 2014
source	ENTEROBACTERIA PHAGE LAMBDA
experiment	X-ray (resolution=2.38, R-factor=?)
structural superfamily	Restriction endonuclease-like;
reference complex	3sm4_B
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 4wuz_A interface= mtpdiilqrtgidvraveqgddawhklrlgvitasevhnviakprsgkkwpdmkmsyfhtllaevctgvapevnakalawgkqyendartlfeftsgvnvtespiiyrdesmrtacspdglcsdgnglelkcpftsrdfmkfrlggfeaiksaymaqvqysmwvtrknawyfanydprmkreglhyvvierdekymasfdeivpefiekmdealaeigfvfgeqwr > 4wuz_B interface=53,73,75,77,78,151, mtpdiilqrtgidvraveqgddawhklrlgvitasevhnviakprsgkkwpdMkmsyfhtllaevctgvapeVnAkALawgkqyendartlfeftsgvnvtespiiyrdesmrtacspdglcsdgnglelkcpftsrdfmkfrlggfeaiKsaymaqvqysmwvtrknawyfanydprmkreglhyvvierdekymasfdeivpefiekmdealaeigfvfgeqwr > 4wuz_C interface=44, tpdiilqrtgidvraveqgddawhklrlgvitasevhnviakpRsgkkwpdmkmsyfhtllaevctgvapevnakalawgkqyendartlfeftsgvnvtespiiyrdesmrtacspdglcsdgnglelkcpftsrdfmkfrlggfeaiksaymaqvqysmwvtrknawyfanydprmkreglhyvvierdekymasfdeivpefiekmdealaeigfvfgeqwr
interface signature	/MVAALK/R

Estimated binding specificities ?

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# IC=4.581 IC/col=0.458 n_of_columns=10

specificity:

A |   0  24  57  20  24  24  24  96   0  13
C |  96  24  13  50  24  24  24   0  96  48
G |   0  24  13  13  24  24  24   0   0  20
T |   0  24  13  13  24  24  24   0   0  15

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updated Wed Jun 24 23:05:05 2026