| structure name | CRYSTAL STRUCTURE OF T. AQUATICUS TRANSCRIPTION INITIATION COMPLEX CONTAINING BUBBLE PROMOTER AND RNA (RNA POLYMERASE SIGMA FACTOR SIGA) |
| reference | Darst et al. Elife 4 ? 2015 |
| source | THERMUS AQUATICUS |
| experiment | X-ray (resolution=4.00, R-factor=0.282) |
| structural superfamily | Sigma2 domain of RNA polymerase sigma factors;Sigma3 and sigma4 domains of RNA polymerase sigma factors; |
| sequence family | Sigma70 region 3; Sigma70 region 2; Sigma70, region 4; Sigma70 factor, region 12; |
| redundant complexes | 4xlr 4xls 4xlp 4xlq |
| links to other resources | NAKB  PDIdb DNAproDB |
| protein sequence | |
| interface signature | DVRLHLLENRLYFFERFKSTYTWWRQNRRVHEIRRAIDESFLTRERRQ |
Estimated binding specificities ?
| contact |  |
A | 73 0 0 0 0 96 73 0 96 96 0 0 96 7 96 24 24 24 24 24 24 24 24 24 24 24 24 9 0 0 0 96 96 0 C | 9 0 0 0 0 0 7 0 0 0 0 96 0 75 0 24 24 24 24 24 24 24 24 24 24 24 24 7 0 0 96 0 0 0 G | 7 96 96 96 0 0 9 0 0 0 96 0 0 7 0 24 24 24 24 24 24 24 24 24 24 24 24 7 96 0 0 0 0 96 T | 7 0 0 0 96 0 7 96 0 0 0 0 0 7 0 24 24 24 24 24 24 24 24 24 24 24 24 73 0 96 0 0 0 0scan! |
Dendrogram of similar interfaces ?
matrix formatDGVGRGLGHG--LTLTET--NTRGLT------YA--------FG--FAEA--RAFAKTSTTAYATCWTWTRCQTNARG----RT--VGHT--ECIT----RARA--AT--------IG--DGEG--SG--FG----LT--TTRGECRCRTQC-------- L +4xln_F +------2 DGVGRGLG--IGLT--ET--NTRGLT------------------KTFAEA--RAFA--SATAYATA--WTRA--------------------------------------------IG------DG----FG---------------------------- ! +6kqf_F +-7 DGVGRGLG----LT--ET--NTRGLT------------RC------FADA--KAYA--SCTAYATCWTWT--QT------------VTHT--EA------RCRCEC--EGIASAQAIC----EGDGSG--FG--------TTRGECRTRCQT-------- L ! ! +6edt_F ! +------1 ------------LT--ET--NTRTLT--------------------FADA--KAYAKTSTTAYATCWTWC--QCTARG--------VTHT--EC------------------------------------------LG--TTRGECRCRTQT-------- L ! +5vi8_F +---------8 --------------------NTRTLT----------------LA--FADA--RA--RTSCTAYATCWTWC--QCEARG--------ITHG--KC------------------------------------------------RGET--RC---------- L ! ! +6omf_F ! ! +---3 --------------------NTRTLT--------------------FADA--------STTCYATTWTWG--QA--RG----------------------------------------------------------------RCEC----QT-------- ! ! ! +6wmr_Z +---9 +---6 ----------------------PGLGRAHCLG----VTRA------------QATA----TAYA--QARC----LC----LT--DTRT--RT------------------LG----WARGET----DAIA------------------------------ L ! ! ! +-6pmi_F ! ! +--5 --------------------NTRGLT----------NCRT--FT--FAEA--RAYA--STTAYATTWTWT--QTTART----------HG--EA--NTNT--RT------------IG------------FG----LT--TTRGECRTRTQT-------- L +-10 ! +-6xl5_F ! ! ! ------------------AT--RT----------VA--RT----------RA------STTAYATAWA--RAQTTARGIA--------HT--EA----------------------IG----------LGFG--------TT--ECRT--QT-------- L ! ! +------------------7f75_F ! ! ----------------------DGQG--------LG--MARTPG--FTRT----TTNTKGAGWTYGRT----------------------------------------------------------------PCFCYG--------TGMGSG----RGQC L +-12 +----------------------5zx2_F ! ! ----------------------------------------------------------------------------------------------------------------------------------RG---------------------------- ! ! +------------------------6jcy_F ! +-11 ----------------------------------------------------------------------------------------------------------------------------------------LT--TTRGETRC--RCQC------ L -13 ! +6ido_B ! +-----------------------4 ----------------------------------------------------------------------------------------------------------------------------------------LG--------TAKGTA--HTRG-- L ! +6jhe_A ! ----------------------------------------------------------------------------------------------------------------------------------------LTETTTRAECRCRCQC-------- L +--------------------------3n97_A |
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updated Mon Dec 18 11:32:34 2023