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structure nameCRYSTAL STRUCTURE OF MUTY BOUND TO ITS ANTI-SUBSTRATE WITH THE DISULFIDE CROSS-LINKER REDUCED
(AG-specific adenine glycosylase)
referenceVerdine et al. J.Biol.Chem. 290 17096 2015
sourceGeobacillus stearothermophilus
experimentX-ray (resolution=2.32, R-factor=0.191)
structural superfamilyDNA-glycosylase;Nudix;
sequence familyHhHGPD superfamily base excision DNA r; Helixhairpinhelix motif; Ironsulfur binding domain of endonucle;
reference complex8dvp_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQQRYMRRSH

Estimated binding specificities ?

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# IC=2.715 IC/col=0.453 n_of_columns=6 specificity:   
A |   0  24  13   7   9  42
C |  96  24  13   7  11  18
G |   0  24  13  75  67  18
T |   0  24  57   7   9  18
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updated Thu Sep 12 20:22:17 2024