interface graph thumbnail
legend  pdf

structure nameQUINOLONE(MOXIFLOXACIN)-DNA CLEAVAGE COMPLEX OF TOPOISOMERASE IV FROM S. PNEUMONIAE
referenceCrevel et al. 'To ? ? ?
experimentX-ray (resolution=3.44, R-factor=0.183)
structural superfamilyType II DNA topoisomerase;
sequence familyDNA gyrase/topoisomerase IV, subunit A; DNA gyrase B subunit, carboxyl terminus; Toprim domain;
multimeric complexes4z3o_AB
reference complex4z4q_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKYRSRI

Estimated binding specificities ?

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# IC=2.603 IC/col=0.651 n_of_columns=4 specificity:   
A |  12  16   0  84
C |  12  19  96   4
G |  12  16   0   4
T |  60  45   0   4
scan!

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updated Mon Dec 18 11:44:53 2023