5bs8_ABCD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A TOPOISOMERASE II COMPLEX
reference	Williamson et al. Proc.Natl.Acad.Sci.USA 113 1706 2016
experiment	X-ray (resolution=2.40, R-factor=?)
structural superfamily	Type II DNA topoisomerase;
reference complex	5bs8_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5bs8_A interface=17,77,114,166, iepvdieqemqrsyidYamsvivgralpevrdglkpvhrrvlyamfdsgfrpdrshaksarsvaetmgnyhphgdaSiydslvrmaqpwslryplvdgqgnfgspgndppaamRtearltplamemlreideetvdfipnydgrvqeptvlpsrfpnllangsggIavgmatnipphnlreladavfwalenhdadeeetlaavmgrvkgpdfptaglivgsqgtadayktgrgsirmrgvveveedsrgrtslvitelpyqvnhdnfitsiaeqvrdgklagisniedqssdrvglrivieikrdavakvvinnlykhtqlqtsfganmlaivdgvprtlrldqliryyvdhqldvivrrttyrlrkanerahilrglvkaldaldevialirasetvdiaraglielldideiqaqaildmqlrrlaalerqriiddlakieaeiadledilakperqrgivrdelaeivdrhgddrrtriiai > 5bs8_B interface=54, alvrrkglpgkladcrstdprkselyvvegdsaggsaksgrdsmfqailplrgKiinvekaridrvlkntevqaiitalgtgihdefdigklryhkivlmadadvdgqhistllltllfrfmrplienghvflaqpplyklkwqrsdpefaysdrerdglleaglkagkkinkedgiqrykglgemdakelwettmdpsvrvlrqvtlddaaaadelfsilmgedvdarrsfitrnakdvrfldv > 5bs8_C interface=17,114,166, iepvdieqemqrsyidYamsvivgralpevrdglkpvhrrvlyamfdsgfrpdrshaksarsvaetmgnyhphgdasiydslvrmaqpwslryplvdgqgnfgspgndppaamRtearltplamemlreideetvdfipnydgrvqeptvlpsrfpnllangsggIavgmatnipphnlreladavfwalenhdadeeetlaavmgrvkgpdfptaglivgsqgtadayktgrgsirmrgvveveedsrgrtslvitelpyqvnhdnfitsiaeqvrdgklagisniedqssdrvglrivieikrdavakvvinnlykhtqlqtsfganmlaivdgvprtlrldqliryyvdhqldvivrrttyrlrkanerahilrglvkaldaldevialirasetvdiaraglielldideiqaqaildmqlrrlaalerqriiddlakieaeiadledilakperqrgivrdelaeivdrhgddrrtriiai > 5bs8_D interface=56, nalvrrksglpgkladcrstdprkselyvvegdsaggsaksgrdsmfqailplrgKiinvekaridrvlkntevqaiitalgtgihdefdigklryhkivlmadadvdgqhistllltllfrfmrplienghvflaqpplyklkwqrsdpefaysdrerdglleaglkagkkinkedgiqrykglgemdakelwettmdpsvrvlrqvtlddaaaadelfsilmgedvdarrsfitrnakdvrfldv
interface signature	YSRI/K/YRI/K

Estimated binding specificities ?

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# IC=7.588 IC/col=0.542 n_of_columns=14

specificity:

A |   0   0  24  88  24  24  24  24  16  48   8  24   0  96
C |   0   0  24   0  24  24  24  24  56  16   0  24  96   0
G |   0  96  24   8  24  24  24  24   8  16   8  24   0   0
T |  96   0  24   0  24  24  24  24  16  16  80  24   0   0

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updated Mon Jan 5 14:49:39 2026