5bta_ABCD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A TOPOISOMERASE II COMPLEX
reference	Williamson et al. Proc.Natl.Acad.Sci.USA 113 1706 2016
experiment	X-ray (resolution=2.55, R-factor=?)
structural superfamily	Type II DNA topoisomerase;
reference complex	5bs8_A
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5bta_A interface=17,76,77,114,166, iepvdieqemqrsyidYamsvivgralpevrdglkpvhrrvlyamfdsgfrpdrshaksarsvaetmgnyhphgdSSiydslvrmaqpwslryplvdgqgnfgspgndppaamRtearltplamemlreideetvdfipnydgrvqeptvlpsrfpnllangsggIavgmatnipphnlreladavfwalenhdadeeetlaavmgrvkgpdfptaglivgsqgtadayktgrgsirmrgvveveedsrgrtslvitelpyqvnhdnfitsiaeqvrdgklagisniedqssdrvglrivieikrdavakvvinnlykhtqlqtsfganmlaivdgvprtlrldqliryyvdhqldvivrrttyrlrkanerahilrglvkaldaldevialirasetvdiaraglielldideiqaqaildmqlrrlaalerqriiddlakieaeiadledilakperqrgivrdelaeivdrhgddrrtriiai > 5bta_B interface=54, alvrrkglpgkladcrstdprkselyvvegdsaggsaksgrdsmfqailplrgKiinvekaridrvlkntevqaiitalgtgihdefdigklryhkivlmadadvdgqhistllltllfrfmrplienghvflaqpplyklkwqrsdpefaysdrerdglleaglkagkkinkedgiqrykglgemdakelwettmdpsvrvlrqvtlddaaaadelfsilmgedvdarrsfitrnakdvrfldv > 5bta_C interface=77,114,166, iepvdieqemqrsyidyamsvivgralpevrdglkpvhrrvlyamfdsgfrpdrshaksarsvaetmgnyhphgdsSiydslvrmaqpwslryplvdgqgnfgspgndppaamRtearltplamemlreideetvdfipnydgrvqeptvlpsrfpnllangsggIavgmatnipphnlreladavfwalenhdadeeetlaavmgrvkgpdfptaglivgsqgtadayktgrgsirmrgvveveedsrgrtslvitelpyqvnhdnfitsiaeqvrdgklagisniedqssdrvglrivieikrdavakvvinnlykhtqlqtsfganmlaivdgvprtlrldqliryyvdhqldvivrrttyrlrkanerahilrglvkaldaldevialirasetvdiaraglielldideiqaqaildmqlrrlaalerqriiddlakieaeiadledilakperqrgivrdelaeivdrhgddrrtriiai > 5bta_D interface=56, nalvrrksglpgkladcrstdprkselyvvegdsaggsaksgrdsmfqailplrgKiinvekaridrvlkntevqaiitalgtgihdefdigklryhkivlmadadvdgqhistllltllfrfmrplienghvflaqpplyklkwqrsdpefaysdrerdglleaglkagkkinkedgiqrykglgemdakelwettmdpsvrvlrqvtlddaaaadelfsilmgedvdarrsfitrnakdvrfldv
interface signature	YSSRI/K/SRI/K

Estimated binding specificities ?

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# IC=9.185 IC/col=0.656 n_of_columns=14

specificity:

A |   0   0  24  94   1  65  24  24  13  65   9  24   0  96
C |   0   0  24   0   1  13  24  24  53  17  17  24  96   0
G |   0  96  24   1   1  17  24  24  17  11  11  24   0   0
T |  96   0  24   1  93   1  24  24  13   3  59  24   0   0

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updated Thu Jun 25 02:20:41 2026