5btg_ABCD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A TOPOISOMERASE II COMPLEX
reference	Williamson et al. Proc.Natl.Acad.Sci.USA 113 1706 2016
experiment	X-ray (resolution=2.50, R-factor=?)
structural superfamily	Type II DNA topoisomerase;
reference complex	5bs8_A 5bs8_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5btg_A interface=17,77,114,166, iepvdieqemqrsyidYamsvivgralpevrdglkpvhrrvlyamfdsgfrpdrshaksarsvaetmgnyhphgdaSiydslvrmaqpwslryplvdgqgnfgspgndppaamRtearltplamemlreideetvdfipnydgrvqeptvlpsrfpnllangsggIavgmatnipphnlreladavfwalenhdadeeetlaavmgrvkgpdfptaglivgsqgtadayktgrgsirmrgvveveedsrgrtslvitelpyqvnhdnfitsiaeqvrdgklagisniedqssdrvglrivieikrdavakvvinnlykhtqlqtsfganmlaivdgvprtlrldqliryyvdhqldvivrrttyrlrkanerahilrglvkaldaldevialirasetvdiaraglielldideiqaqaildmqlrrlaalerqriiddlakieaeiadledilakperqrgivrdelaeivdrhgddrrtriiai > 5btg_B interface=54, alvrrkglpgkladcrstdprkselyvvegdsaggsaksgrdsmfqailplrgKiinvekaridrvlkntevqaiitalgtgihdefdigklryhkivlmadadvdgqhistllltllfrfmrplienghvflaqpplyklkwqrsdpefaysdrerdglleaglkagkkinkedgiqrykglgemdakelwettmdpsvrvlrqvtlddaaaadelfsilmgedvdarrsfitrnakdvrfldv > 5btg_C interface=77,114,166, iepvdieqemqrsyidyamsvivgralpevrdglkpvhrrvlyamfdsgfrpdrshaksarsvaetmgnyhphgdaSiydslvrmaqpwslryplvdgqgnfgspgndppaamRtearltplamemlreideetvdfipnydgrvqeptvlpsrfpnllangsggIavgmatnipphnlreladavfwalenhdadeeetlaavmgrvkgpdfptaglivgsqgtadayktgrgsirmrgvveveedsrgrtslvitelpyqvnhdnfitsiaeqvrdgklagisniedqssdrvglrivieikrdavakvvinnlykhtqlqtsfganmlaivdgvprtlrldqliryyvdhqldvivrrttyrlrkanerahilrglvkaldaldevialirasetvdiaraglielldideiqaqaildmqlrrlaalerqriiddlakieaeiadledilakperqrgivrdelaeivdrhgddrrtriiai > 5btg_D interface=56, nalvrrksglpgkladcrstdprkselyvvegdsaggsaksgrdsmfqailplrgKiinvekaridrvlkntevqaiitalgtgihdefdigklryhkivlmadadvdgqhistllltllfrfmrplienghvflaqpplyklkwqrsdpefaysdrerdglleaglkagkkinkedgiqrykglgemdakelwettmdpsvrvlrqvtlddaaaadelfsilmgedvdarrsfitrnakdvrfldv
interface signature	YSRI/K/SRI/K

Estimated binding specificities ?

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# IC=7.669 IC/col=0.548 n_of_columns=14

specificity:

A |   0   0  24  60  16  24  24  24  12  60   0  24   0  96
C |   0   0  24  12  12  24  24  24  12  12   4  24  96   0
G |   0  96  24  12  12  24  24  24  12  12   0  24   0   0
T |  96   0  24  12  56  24  24  24  60  12  92  24   0   0

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updated Tue Sep 10 02:43:18 2024