5bti_ABCD : 3D-footprint complex

structure name	CRYSTAL STRUCTURE OF A TOPOISOMERASE II COMPLEX
reference	Williamson et al. Proc.Natl.Acad.Sci.USA 113 1706 2016
experiment	X-ray (resolution=2.50, R-factor=?)
structural superfamily	Type II DNA topoisomerase;
reference complex	5bs8_A 5bs8_D
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5bti_A interface=17,76,77,166, iepvdieqemqrsyidYamsvivgralpevrdglkpvhrrvlyamfdsgfrpdrshaksarsvaetmgnyhphgdSSiydslvrmaqpwslryplvdgqgnfgspgndppaamrtearltplamemlreideetvdfipnydgrvqeptvlpsrfpnllangsggIavgmatnipphnlreladavfwalenhdadeeetlaavmgrvkgpdfptaglivgsqgtadayktgrgsirmrgvveveedsrgrtslvitelpyqvnhdnfitsiaeqvrdgklagisniedqssdrvglrivieikrdavakvvinnlykhtqlqtsfganmlaivdgvprtlrldqliryyvdhqldvivrrttyrlrkanerahilrglvkaldaldevialirasetvdiaraglielldideiqaqaildmqlrrlaalerqriiddlakieaeiadledilakperqrgivrdelaeivdrhgddrrtriiai > 5bti_B interface=54, alvrrkglpgkladcrstdprkselyvvegdsaggsaksgrdsmfqailplrgKiinvekaridrvlkntevqaiitalgtgihdefdigklryhkivlmadadvdgqhistllltllfrfmrplienghvflaqpplyklkwqrsdpefaysdrerdglleaglkagkkinkedgiqrykglgemdakelwettmdpsvrvlrqvtlddaaaadelfsilmgedvdarrsfitrnakdvrfldv > 5bti_C interface=77,166, iepvdieqemqrsyidyamsvivgralpevrdglkpvhrrvlyamfdsgfrpdrshaksarsvaetmgnyhphgdsSiydslvrmaqpwslryplvdgqgnfgspgndppaamrtearltplamemlreideetvdfipnydgrvqeptvlpsrfpnllangsggIavgmatnipphnlreladavfwalenhdadeeetlaavmgrvkgpdfptaglivgsqgtadayktgrgsirmrgvveveedsrgrtslvitelpyqvnhdnfitsiaeqvrdgklagisniedqssdrvglrivieikrdavakvvinnlykhtqlqtsfganmlaivdgvprtlrldqliryyvdhqldvivrrttyrlrkanerahilrglvkaldaldevialirasetvdiaraglielldideiqaqaildmqlrrlaalerqriiddlakieaeiadledilakperqrgivrdelaeivdrhgddrrtriiai > 5bti_D interface=56, nalvrrksglpgkladcrstdprkselyvvegdsaggsaksgrdsmfqailplrgKiinvekaridrvlkntevqaiitalgtgihdefdigklryhkivlmadadvdgqhistllltllfrfmrplienghvflaqpplyklkwqrsdpefaysdrerdglleaglkagkkinkedgiqrykglgemdakelwettmdpsvrvlrqvtlddaaaadelfsilmgedvdarrsfitrnakdvrfldv
interface signature	YSSI/K/SI/K

Estimated binding specificities ?

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# IC=7.269 IC/col=0.519 n_of_columns=14

specificity:

A |   0   0  24  45  16  24  24  24  24  58   0  24   0  96
C |   0   0  24  19  11  24  24  24  24  11   5  24  96   0
G |   0  96  24  16   5  24  24  24  24  16   0  24   0   0
T |  96   0  24  16  64  24  24  24  24  11  91  24   0   0

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updated Sat Dec 14 00:45:01 2024