interface graph thumbnail
legend  pdf

structure nameE. COLI RNA POLYMERASE ALPHA SUBUNIT CTD IN COMPLEX WITH CAP AND DNA: A(5)-TRACT BINDING SITE FOR ALPHA CTD
(CAMP-ACTIVATED GLOBAL TRANSCRIPTIONAL REGULATOR CRP)
referenceNapoli et al. Biochemistry ? ? 2020
sourceESCHERICHIA COLI (STRAIN K12) / ESCHERICHIA COLI (STRAIN K12)
experimentX-ray (resolution=5.01, R-factor=0.182)
structural superfamilycAMP-binding domain-like;"Winged helix" DNA-binding domain;
sequence familyCyclic nucleotidebinding domain; Bacterial regulatory proteins, crp famil;
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQSRER

Estimated binding specificities ?

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# IC=4.475 IC/col=0.895 n_of_columns=5 specificity:   
A |   0  13  13   0  96
C |   0  16  13   0   0
G |   0  54  13  96   0
T |  96  13  57   0   0
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updated Fri Jan 9 02:52:16 2026