interface graph thumbnail
legend  pdf

structure nameTRANSCRIPTION FACTOR-DNA COMPLEX
(Signal transducer and activator of transcription 6)
referenceOuyang et al. Proc.Natl.Acad.Sci.USA 113 13015 2016
sourceHomo sapiens
experimentX-ray (resolution=3.20, R-factor=0.211)
structural superfamilyp53-like transcription factors;SH2 domain;STAT;
sequence familySTAT protein, DNA binding domain; STAT protein, allalpha domain; SH2 domain;
multimeric complexes4y5w_AC 4y5w_BD 5d39_AC 5d39_BD
reference complex4y5w_B
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureKVHNQ

Estimated binding specificities ?

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# IC=2.635 IC/col=0.659 n_of_columns=4 specificity:   
A |   9   9  11   0
C |   9   9  67  96
G |  11  11   9   0
T |  67  67   9   0
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updated Thu Sep 12 21:03:19 2024