interface graph thumbnail
legend  pdf

structure nameHUMAN APE1 E96Q/D210N MISMATCH SUBSTRATE COMPLEX
(DNA-apurinic or apyrimidinic site lyase)
referenceFreudenthal et al. Nat.Struct.Mol.Biol. 22 924 2015
sourceHomo sapiens
experimentX-ray (resolution=1.85, R-factor=0.161)
structural superfamilyDNase I-like;
sequence familyEndonuclease/Exonuclease/phosphatase fa;
reference complex6bow_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureDKYRNNYMMD

Estimated binding specificities ?

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# IC=3.142 IC/col=0.524 n_of_columns=6 specificity:   
A |  16   0  24  13  24   0
C |  54   0  24  13  24   0
G |  13  96  24  57  24  96
T |  13   0  24  13  24   0
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updated Thu Sep 12 21:05:53 2024