interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE ETA EXTENDING AN 1,N6- ETHENODEOXYADENOSINE : DT PAIR BY INSERTING DTMPNPP OPPOSITE TEMPLATE DA
(DNA polymerase eta)
referencePatra et al. J.Biol.Chem. 291 14134 2016
sourceHomo sapiens
experimentX-ray (resolution=2.30, R-factor=0.160)
structural superfamilyDNA/RNA polymerases;Lesion bypass DNA polymerase Y-family, little finger domain;
sequence familyimpB/mucB/samB family;
reference complex3jaa_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQIRSLR

Estimated binding specificities ?

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# IC=2.125 IC/col=0.354 n_of_columns=6 specificity:   
A |   1  10  24  21  52  10
C |  92  10  24  33  14  13
G |   1  66  24  21  14  10
T |   2  10  24  21  16  63
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updated Thu Sep 12 21:06:26 2024