interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE ETA EXTENDING AN 1,N6- ETHENODEOXYADENOSINE : DA PAIR BY INSERTING DTMPNPP OPPOSITE TEMPLATE DA
(DNA polymerase eta)
referencePatra et al. J.Biol.Chem. 291 14134 2016
sourceHomo sapiens
experimentX-ray (resolution=1.79, R-factor=0.167)
structural superfamilyDNA/RNA polymerases;Lesion bypass DNA polymerase Y-family, little finger domain;
sequence familyimpB/mucB/samB family;
reference complex3jaa_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureQIRSLRF

Estimated binding specificities ?

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# IC=4.475 IC/col=0.746 n_of_columns=6 specificity:   
A |  96  13  13  24   0   0
C |   0  13  13  24  96   0
G |   0  13  54  24   0  96
T |   0  57  16  24   0   0
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updated Sun Jun 28 12:37:01 2026