interface graph thumbnail
legend  pdf

structure nameCRYSTAL STRUCTURE OF HUMAN DNA POLYMERASE ETA INSERTING DGMPNPP OPPOSITE O4-METHYLHYMIDINE
(DNA polymerase eta)
referenceOFlaherty et al. 'Chem 7 4896 2016
sourceHomo sapiens
experimentX-ray (resolution=2.35, R-factor=0.175)
structural superfamilyDNA/RNA polymerases;Lesion bypass DNA polymerase Y-family, little finger domain;
sequence familyimpB/mucB/samB family;
reference complex3jaa_A
links to other resourcesNAKB PDBSum PDIdb DNAproDB
protein sequence
interface signatureRSR

Estimated binding specificities ?

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# IC=1.372 IC/col=0.229 n_of_columns=6 specificity:   
A |   4  13  24  24  38  12
C |  81  13  24  24  19  12
G |   7  56  24  24  19  12
T |   4  14  24  24  20  60
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updated Fri Jan 9 03:05:26 2026