5egb_A : 3D-footprint complex

structure name	HUMAN PRDM9 ALLELE-A ZNF DOMAIN WITH ASSOCIATED RECOMBINATION HOTSPOT DNA SEQUENCE II (Histone-lysine N-methyltransferase PRDM9)
reference	Horton et al. 'Genes 30 257 2016
source	Homo sapiens
experiment	X-ray (resolution=1.98, R-factor=0.194)
structural superfamily	beta-beta-alpha zinc fingers;
sequence family	Zinc finger, C2H2 type;
reference complex	5ei9_F
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5egb_A interface=14,15,17,18,21,43,45,46,49,52,70,71,73,74,99,100,101,102,105, ekpyvcrecgrgfSNkSHllRhqrthtgekpyvcrecgrgfrDkSHllRhqRthtgekpyvcrecgrgfRDkSNllshqrthtgekpyvcrecgrgfsNKSHllRhqrtht
interface signature	SNSHRDSHRRRDSNNKSHR

Estimated binding specificities ?

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# IC=16.651 IC/col=1.189 n_of_columns=14

specificity:

A |   0   0   0   0   0  96   0   0   0  82   0   0   0  43
C |   0   0   0  96   0   0   0   0   0  14   0   0  96  13
G |  14  96  96   0   0   0  96  96  96   0  96  96   0  27
T |  82   0   0   0  96   0   0   0   0   0   0   0   0  13

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updated Sat Aug 2 08:35:53 2025