5eh2_E : 3D-footprint complex

structure name	HUMAN PRDM9 ALLELE-A ZNF DOMAIN WITH ASSOCIATED RECOMBINATION HOTSPOT DNA SEQUENCE III (Histone-lysine N-methyltransferase PRDM9)
reference	Horton et al. 'Genes 30 257 2016
source	Homo sapiens
experiment	X-ray (resolution=2.05, R-factor=0.202)
structural superfamily	beta-beta-alpha zinc fingers;
sequence family	Zinc finger, C2H2 type;
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5eh2_E interface=14,16,17,20,42,44,45,48,69,70,72,73,98,99,100,101,104,107, kpyvcrecgrgfsNkSHllRhqrthtgekpyvcrecgrgfrDkSHllRhqrthtgekpyvcrecgrgfRDkSNllshqrthtgekpyvcrecgrgfsNKSHllRhqRtht
interface signature	NSHRDSHRRDSNNKSHRR

Estimated binding specificities ?

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# IC=15.811 IC/col=1.129 n_of_columns=14

specificity:

A |   8   0   0   0   8   0   0   0   0  87   8   0   0  69
C |  11   0  96  96   0  96  96  96   0   1   0  96  96   8
G |   8  96   0   0   8   0   0   0   0   8  88   0   0  11
T |  69   0   0   0  80   0   0   0  96   0   0   0   0   8

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updated Tue Dec 17 01:36:23 2024