5fur_ACGI : 3D-footprint complex

structure name	STRUCTURE OF HUMAN TFIID-IIA BOUND TO CORE PROMOTER DNA
reference	Lopez-Blanco et al. Nature 531 604 2016
source	HOMO SAPIENS
experiment	X-ray (resolution=8.50, R-factor=?)
links to other resources	NAKB PDIdb DNAproDB
protein sequence	> 5fur_A interface=9,11,39,40,54,56,62,64,99,101,130,131,145,147,153,155, sgivpqlqNiVstvnlgckldlktialrarnaeynpkrFAavimrireprttaLiFssgkmVcTgakseeqsrlaarkyarvvqklgfpakfldfkiqNmVgscdvkfpirleglvlthqqfssyepelFPgliyrmikprivlLiFvsgkvVlTgakvraeiyeafeniypilkgfrkt > 5fur_C interface= dtenvvvcQyDkihrsknkwkfhlkdgimnlngrdyifSKaigdaew > 5fur_G interface=253,256,257,267, iiqhsipavelrqpffpthmgpiklrqfhrpplkkysfgalsqpgphsvqpllkhikkkakmreqerqasgggemffmrtpqdltgkdgdlilaeyseengplmmqvgmatkiknyykrkpgkdpgapdckygetvychtspflgslhpgqllqafennlfrapiylhkmpetdfliirtrqgyyirelvdifvvgqqcplfevpgpnskranthirdflqvfiyrlfwkskdrprrirmedikkafpshseSsiRKrlklcadfkRtgmdsnwwvlksdfrlpteeeiramvspeqccayysmiaaeqrlkdagygeksfkiddevrtapwnttrafiaamkgkcllevtgvadptgcgegfsyvkipnksvaehqerykeecqrifdlqnkvlsstevldtd > 5fur_I interface= klthqvvcinninfqrksvvgfveltifptvanlnriklnskqcriyrvrindleaafiynelcikvpselwkhvdelkvlkihinfsldqpkgglhfvvpsvegsmaergahvfscgyqnstrfwfpcvdsyselctwkleftvdaamvavsngdlvetvythdmrkktfhymltiptaasnislaigpfeilvdpymhevthfclpqllpllkhttsylhevfefyeeiltcrypyscfktvfideayveVaaYAsmsifstnlLhsamiidetpltrrclaqslaqqffgcfisrmswsdewvlkgisgyiyglwmkktfgvneyrhwikeeldkivayelktggvllhpifgggkekdnpashlhfsikhphtlsweyysmfqckahlvmrlienrismefmlqvfnkllslastassqkfqshmwsqmlvstsgflksisnvsgkdiqplikqwvdqsgvvkfygsfafnrkrnvleleikqdytspgtqkyvgplkvtvqeldgsfnhtlqieenslkhdipchsksrrnkkkkiplmngeevdmdlsamdadspllwiridpdmsvlrkvefeqadfmwqyqlryerdvvaqqesilalekfptpasrlaltdileqeqcfyrvrmsacfclakiansmvstwtgppamkslftrmfcckscpnivktnnfmsfqsyflqktmpvamallrdvhnlcpkevltfildlikyndnrknkfsdnyyraemidalansvtpavsvnnevrtldnlnpdvrlileeitrflnmekllpsyrhtitvsclrairvlqknghvpsdpalfksyaeyghfvdiriaaleavvdytkvdrsyeelqwllnmiqndpvpyvrhkilnmltknppftknmesplcnealvdqlwklmnsgtshdwrlrcgavdly
interface signature	NVFALFVTNVFPLFVT/QDSK/SRKR/VYAL

Estimated binding specificities ?

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# IC=11.330 IC/col=0.186 n_of_columns=61

specificity:

A |   4  24  24  16  24  24  24  44  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   0   0   0   0   0  92   0  96
C |   8  24  24   4  24  24  24  20  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  92   0   4   0   0   4   0   0
G |   4  24  24  56  24  24  24  16  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   4   0   0   0   0   0   0   0
T |  80  24  24  20  24  24  24  16  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24  24   0  96  92  96  96   0  96   0

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updated Mon Jan 5 16:30:57 2026